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漱口水之战——洗必泰与草本漱口水:一项荟萃分析

The Mouthwash War - Chlorhexidine vs. Herbal Mouth Rinses: A Meta-Analysis.

作者信息

Manipal Sunayana, Hussain Sajjid, Wadgave Umesh, Duraiswamy Prabu, Ravi K

机构信息

Reader, Department of Public Health Dentistry, SRM Dental College , Ramapuram, Chennai, Tamil Nadu, India .

Senior lecturer, Department of Periodontology, Balaji Dental College , Chennai, Tamil nadu, India .

出版信息

J Clin Diagn Res. 2016 May;10(5):ZC81-3. doi: 10.7860/JCDR/2016/16578.7815. Epub 2016 May 1.

Abstract

INTRODUCTION

Mouthwashes are often prescribed in dentistry for prevention and treatment of several oral conditions. In the recent times the use of naturally occurring products what is otherwise known as grandmothers remedy are used on a large scale. This has now called for a newer age of mouth washes but is the new age mouth washes at par with the gold standard or even better than them this study investigates.

AIM

The aim of the present study was to compare the effect of two broad categories of mouth washes namely chlorhexidine and herbal mouth washes.

MATERIALS AND METHODS

Eleven randomized control studies were pooled in for the meta-analysis. The search was done from the Pub Med Central listed studies with the use keywords with Boolean operators (chlorhexidine, herbal, mouth wash, randomized control trials). The fixed effects model was used for analysis.

RESULTS

This meta-analysis brings to light, the fact that a wide range of newer herbal products are now available. As with a plethora of herbal mouthwashes available it is the need of the hour to validate their potential use and recommendation. This study found that only two studies favor the use of herbal products and four studies favor the use of chlorhexidine, of the 11 studies that were analyzed.

CONCLUSION

More studies are required under well controlled circumstances to prove that herbal products can equate or replace the 'gold standard' chlorhexidine. Herbal products are heterogeneous in nature, their use should be advised only with more scientific proof.

摘要

引言

在牙科领域,漱口水常用于预防和治疗多种口腔疾病。近年来,天然产品(即所谓的祖传疗法)的使用得到了广泛推广。这促使漱口水迎来了新的时代,但新时代的漱口水是否能与金标准相当,甚至比金标准更好,本研究对此进行了调查。

目的

本研究的目的是比较两类漱口水的效果,即洗必泰漱口水和草本漱口水。

材料与方法

汇总了11项随机对照研究进行荟萃分析。通过使用带有布尔运算符的关键词(洗必泰、草本、漱口水、随机对照试验)在PubMed Central列出的研究中进行检索。采用固定效应模型进行分析。

结果

这项荟萃分析揭示,现在有各种各样的新型草本产品。鉴于有大量草本漱口水可供选择,当下需要验证它们的潜在用途并给出推荐。在分析的11项研究中,本研究发现只有两项研究支持使用草本产品,四项研究支持使用洗必泰。

结论

需要在严格控制的条件下进行更多研究,以证明草本产品能够等同于或取代“金标准”洗必泰。草本产品性质各异,只有在有更多科学依据的情况下才应建议使用。

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Antimicrobial Efficacy of Extemporaneously Prepared Herbal Mouthwashes.临时配制的草本漱口水的抗菌效果。
Recent Pat Drug Deliv Formul. 2015;9(3):257-61. doi: 10.2174/1872211309666150608095106.

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