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老年人群中小的肾脏肿块:非手术和手术策略的当代治疗方法和比较肿瘤学结果。

Small renal masses in the elderly: Contemporary treatment approaches and comparative oncological outcomes of nonsurgical and surgical strategies.

机构信息

Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Department of Urology, SSB Trauma Center, Firozabad, India.

出版信息

Investig Clin Urol. 2016 Jul;57(4):231-9. doi: 10.4111/icu.2016.57.4.231. Epub 2016 Jul 5.

Abstract

Over the last decades, there has been a significant stage migration in renal cell carcinoma and especially older patients are getting diagnosed more frequently with low stage disease, such as small renal masses ≤4 cm of size. Considering the particular risk profile of an older population, often presenting with a nonnegligible comorbidity profile and progressive renal dysfunction, treatment approaches beyond aggressive radical surgical procedures have come to the fore. We sought to give a contemporary overview of the available different treatment strategies for incidental small renal masses in an elderly population with the focus on comparative oncological outcomes of nonsurgical and surgical modalities.

摘要

在过去的几十年中,肾细胞癌的分期发生了显著变化,尤其是年龄较大的患者越来越频繁地被诊断为低分期疾病,如直径≤4cm 的小肾肿块。考虑到老年人群的特殊风险状况,他们常伴有不可忽视的合并症和进行性肾功能障碍,因此除了激进的根治性手术外,还需要采用其他治疗方法。我们旨在对老年人群中偶然发现的小肾肿块的现有不同治疗策略进行现代综述,重点是比较非手术和手术方式的肿瘤学结果。

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