Hsu Ching-Sheng, Kao Jia-Horng
Division of Gastroenterology, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan; School of Medicine and School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan.
Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Internal Medicine; Department of Medical Research; Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan.
AIDS Rev. 2016 Oct-Dec;18(4):193-197.
Both human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection are important global public health problems with shared transmission routes. Although HIV/HCV coinfection is not uncommon, the prevalence rates vary significantly across different studies and regions. In Taiwan, injection drug users have become the major contributors to the HIV/AIDS epidemic since 2005. Because the prevalence of HCV infection is high in injection drug users, this HIV epidemic is also associated with a significant increase of HIV/HCV coinfection in Taiwan. To control Taiwan's HIV epidemic, Taiwan Centers for Disease Control (CDC) launched a harm-reduction program in 2006. The HIV epidemic, the percentage attributed to injection drug users, and the prevalence of HIV/HCV coinfection gradually declined thereafter. In this article, we aimed to thoroughly examine the current literatures of HIV/HCV coinfection in Taiwan and hope to provide a better understanding of the needs for the management of this coinfection. We conducted a narrative review and searched for literature from PubMed, Ovid MEDLINE, and the Cochrane Library database untill August 2015. Studies relevant to the epidemiology and associated risk factors of HIV/HCV coinfection in Taiwan were examined and discussed.
人类免疫缺陷病毒（HIV）感染和丙型肝炎病毒（HCV）感染都是通过相同传播途径传播的重要全球公共卫生问题。尽管HIV/HCV合并感染并不罕见，但不同研究和地区的患病率差异很大。在台湾，自2005年以来，注射吸毒者已成为HIV/AIDS流行的主要原因。由于注射吸毒者中HCV感染率很高，因此台湾的这一HIV流行也与HIV/HCV合并感染的显著增加有关。为了控制台湾的HIV流行，台湾疾病控制中心（CDC）于2006年启动了一项减少伤害计划。此后，HIV流行、注射吸毒者所占百分比以及HIV/HCV合并感染率逐渐下降。在本文中，我们旨在全面审视台湾目前关于HIV/HCV合并感染的文献，并希望能更好地了解管理这种合并感染的需求。我们进行了一项叙述性综述，并检索了截至2015年8月来自PubMed、Ovid MEDLINE和Cochrane图书馆数据库的文献。对台湾地区与HIV/HCV合并感染的流行病学及相关危险因素相关的研究进行了审查和讨论。
