Ngu Jing Hieng, Goh George Boon Bee, Poh Zhongxian, Soetikno Roy
Singapore General Hospital, Singapore.
Duke-NUS Medical School, Singapore.
Singapore Med J. 2016 Jul;57(7):368-71. doi: 10.11622/smedj.2016119.
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing rapidly with the obesity and diabetes mellitus epidemics. It is rapidly becoming the most common cause of liver disease worldwide. NAFLD can progress to serious complications such as cirrhosis, hepatocellular carcinoma and death. Therefore, it is important to recognise this condition so that early intervention can be implemented. Lifestyle modifications and strict control of metabolic risk factors are the mainstay of treatment. As disease progression is slow in the majority of NAFLD patients, most can be managed well by primary care physicians. NAFLD patients with advanced liver fibrosis should be referred to specialist care for further assessment.
随着肥胖症和糖尿病的流行，非酒精性脂肪性肝病（NAFLD）的患病率正在迅速上升。它正迅速成为全球最常见的肝病病因。NAFLD可进展为严重并发症，如肝硬化、肝细胞癌和死亡。因此，认识到这种疾病很重要，以便能够实施早期干预。生活方式的改变和对代谢危险因素的严格控制是治疗的主要方法。由于大多数NAFLD患者的疾病进展缓慢，大多数患者可由初级保健医生进行良好管理。患有晚期肝纤维化的NAFLD患者应转诊至专科护理进行进一步评估。
