msVolcano：一个用于可视化定量蛋白质组学数据的灵活的网络应用程序。

Singh Sukhdeep, Hein Marco Y, Stewart A Francis

Genomics, Biotechnology Center, Technische Universität Dresden, Dresden, Germany.

Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.

Proteomics. 2016 Sep;16(18):2491-4. doi: 10.1002/pmic.201600167.

UNLABELLED

We introduce msVolcano, a web application for the visualization of label-free mass spectrometric data. It is optimized for the output of the MaxQuant data analysis pipeline of interactomics experiments and generates volcano plots with lists of interacting proteins. The user can optimize the cutoff values to find meaningful significant interactors for the tagged protein of interest. Optionally, stoichiometries of interacting proteins can be calculated. Several customization options are provided to the user for flexibility, and publication-quality outputs can also be downloaded (tabular and graphical).

AVAILABILITY

msVolcano is implemented in R Statistical language using Shiny. It can be accessed freely at http://projects.biotec.tu-dresden.de/msVolcano/.

未标注

我们介绍了msVolcano，这是一个用于可视化无标记质谱数据的网络应用程序。它针对相互作用组学实验的MaxQuant数据分析管道的输出进行了优化，并生成带有相互作用蛋白质列表的火山图。用户可以优化截止值，以找到感兴趣的标记蛋白质的有意义的显著相互作用物。还可以选择计算相互作用蛋白质的化学计量。为用户提供了几种定制选项以增加灵活性，并且还可以下载具有发表质量的输出（表格和图形）。