Cambridge Centre for Proteomics, Cambridge Systems Biology Centre, Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QR, Cambridge, UK.
Bioinformatics. 2012 Jan 15;28(2):288-9. doi: 10.1093/bioinformatics/btr645. Epub 2011 Nov 22.
MSnbase is an R/Bioconductor package for the analysis of quantitative proteomics experiments that use isobaric tagging. It provides an exploratory data analysis framework for reproducible research, allowing raw data import, quality control, visualization, data processing and quantitation. MSnbase allows direct integration of quantitative proteomics data with additional facilities for statistical analysis provided by the Bioconductor project.
MSnbase is implemented in R (version ≥ 2.13.0) and available at the Bioconductor web site (http://www.bioconductor.org/). Vignettes outlining typical workflows, input/output capabilities and detailing underlying infrastructure are included in the package.
MSnbase 是一个用于分析使用等重标记的定量蛋白质组学实验的 R/Bioconductor 包。它为可重复研究提供了一个探索性数据分析框架，允许导入原始数据、进行质量控制、可视化、数据处理和定量分析。MSnbase 允许将定量蛋白质组学数据与 Bioconductor 项目提供的用于统计分析的其他功能直接集成。
MSnbase 是用 R（版本≥2.13.0）实现的，可在 Bioconductor 网站（http://www.bioconductor.org/）上获得。该软件包中包含了概述典型工作流程、输入/输出功能以及详细描述基础结构的实例。
