Oshitani N, Kitano A, Nakamura S, Obata A, Hashimura H, Hiki M, Matsumoto T, Okawa K, Kobayashi K
Third Department of Internal Medicine, Osaka City University Medical School, Japan.
Digestion. 1989;42(1):39-43. doi: 10.1159/000199823.
Thirty patients with ulcerative colitis who had been followed clinically for more than 5 years were studied. Patients with total or left-sided colitis were investigated to evaluate the significance of rectal sparing in the prognosis of the disease. Patients were divided into two groups, one with complete or relative sparing of the rectum and the other with homogeneous lesions ranging from the rectum to the proximal colon based on endoscopic findings. The administration of topical corticosteroids seemed to have little effect on rectal sparing. However, the relapse index was significantly higher in patients with rectal sparing. The intractability index, representing the ratio of the duration of the active stage to the investigation period, was also higher, though not significantly so, in this group. The results suggest that rectal sparing may give information about intractability or a tendency to relapse.
对30例临床随访超过5年的溃疡性结肠炎患者进行了研究。对全结肠炎或左侧结肠炎患者进行调查,以评估直肠保留在疾病预后中的意义。根据内镜检查结果,将患者分为两组,一组直肠完全或相对保留,另一组从直肠到近端结肠有均匀病变。局部使用皮质类固醇似乎对直肠保留影响不大。然而,直肠保留患者的复发指数明显更高。代表活动期持续时间与调查期之比的难治性指数在该组中也较高,尽管不显著。结果表明,直肠保留可能提供有关难治性或复发倾向的信息。