[Siderophilic erythrokaryocytes of the bone marrow at different periods in the course of acute leukemia].

Investigation of the degree of granular siderophilia of bone marrow erythrokaryocytes in 180 adult patients with different patterns and variants of acute leukemia promoted the development of a new assessment criterion, a coefficient of the mean granular distribution. During the diagnosis establishment before the institution of the cytostatic therapy, the significant differences were revealed in the degree of siderophilia of erythrokaryocytes of the bone marrow in lymphoblastic and myeloblastic leukemia as were those between M5a and M5b subvariants of acute leukemias. The differences thus found can be used in medical practice as an additional differential-diagnostic test in cytochemical typing of acute leukemias.