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腹腔镜胰体尾切除术中转开腹的相关因素及后果:单中心初步经验

Factors associated with and consequences of open conversion after laparoscopic distal pancreatectomy: initial experience at a single institution.

作者信息

Goh Brian K P, Chan Chung Yip, Lee Ser Yee, Chan Weng Hoong, Cheow Peng Chung, Chow Pierce K H, Ooi London L P J, Chung Alexander Y F

机构信息

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.

Duke-NUS Graduate Medical School, Singapore.

出版信息

ANZ J Surg. 2017 Dec;87(12):E271-E275. doi: 10.1111/ans.13661. Epub 2016 Jul 21.

Abstract

BACKGROUND

Laparoscopic distal pancreatectomy (LDP) is increasingly adopted today. This study aims to determine factors associated with and consequences of open conversion after LDP.

METHODS

Retrospective review of the first 40 consecutive LDP performed for pancreatic tumors from 2006 to 2015 was performed. Individual surgeon volume was stratified by ≤5 versus >5 cases and institution experience was stratified by two time periods 2006-2010 and 2011-2015.

RESULTS

Two high-volume surgeons performed 19 cases with an average case volume of ≥2/year whereas 10 low-volume surgeons performed 21 cases with an average case volume of <1/year. Median age of patients was 57.6 (range, 21-78) years. LDP was performed for malignancy in four (10%) patients. The median tumor size was 25 (range, 8-75) mm. Eight patients (20%) underwent subtotal pancreatectomies and seven (17.5%) had concomitant surgeries. Eleven (27.5%) LDP were spleen-saving procedures. Ten (25%) procedures were converted to open. Twenty-nine (72.5%) patients experienced 90-day/in-hospital morbidity of which eight (20%) were major (>grade II). There were 24 (60%) pancreatic fistulas of which 10 (25%) were grade B. Univariate analyses demonstrated that splenectomy (10 (34.5%) versus 0, P = 0.025), individual surgeon volume (<5 cases) (8 (38.1%) versus 2 (10.15%), P = 0.044) and institution experience (5 (55.6%) versus 5 (16.1%), P = 0.016) were factors associated with open conversion after LDP. Open conversion was associated with an increased rate of intra-operative blood transfusion (P = 0.053).

CONCLUSIONS

Splenectomy, institution experience and individual surgeon volume were the factors associated with open conversion after LDP.

摘要

背景

如今,腹腔镜远端胰腺切除术(LDP)的应用越来越广泛。本研究旨在确定与LDP术后中转开腹相关的因素及其后果。

方法

对2006年至2015年连续进行的首例40例因胰腺肿瘤而行LDP的病例进行回顾性分析。将个体手术医生的手术量分为≤5例和>5例两组,将机构经验分为2006 - 2010年和2011 - 2015年两个时间段。

结果

两名高手术量医生进行了19例手术,平均每年≥2例;而10名低手术量医生进行了21例手术,平均每年<1例。患者的中位年龄为57.6岁(范围21 - 78岁)。4例(10%)患者因恶性肿瘤行LDP。肿瘤中位大小为25mm(范围8 - 75mm)。8例(20%)患者接受了胰腺次全切除术,7例(17.5%)患者同时进行了其他手术。11例(27.5%)LDP为保脾手术。10例(25%)手术中转开腹。29例(72.5%)患者发生90天内/住院期间并发症,其中8例(20%)为严重并发症(>Ⅱ级)。有24例(60%)发生胰瘘,其中10例(25%)为B级。单因素分析表明,脾切除术(10例(34.5%)对0例,P = 0.025)、个体手术医生手术量(<5例)(8例(38.1%)对2例(10.15%),P = 0.044)和机构经验(5例(55.6%)对5例(16.1%),P = 0.016)是与LDP术后中转开腹相关的因素。中转开腹与术中输血率增加相关(P = 0.053)。

结论

脾切除术、机构经验和个体手术医生手术量是与LDP术后中转开腹相关的因素。

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