Suppr超能文献

转化性腹腔镜胰体尾切除术:对患者结局和总费用有影响吗?

Converted laparoscopic distal pancreatectomy: is there an impact on patient outcome and total cost?

机构信息

Division of Pancreatic Surgery, IRCCS, Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.

Department of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, University of Bologna, S.Orsola-Malpighi Hospital, Via Massarenti n.9, 40138, Bologna, Italy.

出版信息

Langenbecks Arch Surg. 2022 Jun;407(4):1499-1506. doi: 10.1007/s00423-021-02427-y. Epub 2022 Feb 7.

Abstract

PURPOSE

Recent studies have reported worse outcomes of converted laparoscopic distal pancreatectomy (CLDP) with respect to total laparoscopic (TLDP) and open (ODP). The aim of the study was to evaluate the impact of conversion on patient outcome and on total cost.

METHODS

Patients requiring a conversion (CLDP) were compared with both TLDP and ODP patients. The relevant patient- and tumour-related variables were collected for each patient. Both intra and postoperative data were extracted. Propensity score matching (PSM) analysis was carried out to equate the groups compared.

RESULTS

Two hundred and five patients underwent DP, 105 (51.2%) ODPs, 81 (39.5%) TLDPs, and 19 (9.3%) CLDPs. After PSM, 19 CLDPs, 38 TLDPs, and 38 ODPs were compared. Patients who underwent CLDP showed a significantly longer operative time (P < 0.001), and an increase in blood loss (P = 0.032) and total cost (P = 0.034) with respect to TLDP, and a significantly longer operative time (P < 0.001), less frequent postoperative morbidity (P = 0.050), and a higher readmission rate (P = 0.035) with respect to ODP.

CONCLUSION

Total laparoscopic pancreatectomy was superior regarding operative findings and total costs with respect to CLDP; ODP showed a higher postoperative morbidity rate and a lower readmission rate with respect to CLDP. However, the reasons for the readmission of patients who underwent CLDP were mainly related to postoperative pancreatic fistula (POPF) grade B which is usually due to pancreas texture. Thus, the majority of distal pancreatectomies can be started using a minimally invasive approach, performing an early conversion if necessary.

摘要

目的

最近的研究报告显示,与完全腹腔镜(TLDP)和开放(ODP)相比,转化后的腹腔镜胰体尾切除术(CLDP)的结局更差。本研究旨在评估转化对患者结局和总费用的影响。

方法

将需要转化的患者(CLDP)与 TLDP 和 ODP 患者进行比较。收集每位患者的相关患者和肿瘤相关变量。提取术中及术后数据。进行倾向评分匹配(PSM)分析以均衡比较组。

结果

205 例患者行 DP,其中 105 例(51.2%)为 ODP,81 例(39.5%)为 TLDP,19 例(9.3%)为 CLDP。PSM 后,19 例 CLDP、38 例 TLDP 和 38 例 ODP 进行比较。与 TLDP 相比,行 CLDP 的患者手术时间明显延长(P<0.001),术中出血量增加(P=0.032),总费用增加(P=0.034),与 ODP 相比,手术时间明显延长(P<0.001),术后并发症发生率较低(P=0.050),再入院率较高(P=0.035)。

结论

与 CLDP 相比,TLDP 在手术结果和总费用方面具有优势;与 CLDP 相比,ODP 的术后并发症发生率较高,再入院率较低。然而,行 CLDP 的患者再入院的主要原因是术后胰瘘(POPF)分级 B,这通常与胰腺质地有关。因此,大多数胰体尾切除术可以采用微创方式开始,如果需要,可以尽早进行转化。

相似文献

1
Converted laparoscopic distal pancreatectomy: is there an impact on patient outcome and total cost?
Langenbecks Arch Surg. 2022 Jun;407(4):1499-1506. doi: 10.1007/s00423-021-02427-y. Epub 2022 Feb 7.
2
Laparoscopic versus open distal pancreatectomy: a single centre propensity score matching analysis.
Updates Surg. 2021 Oct;73(5):1747-1755. doi: 10.1007/s13304-021-01039-x. Epub 2021 Apr 3.
4
Impact of laparoscopy in patients aged over 70 years requiring distal pancreatectomy: a French multicentric comparative study.
Surg Endosc. 2018 Jul;32(7):3164-3173. doi: 10.1007/s00464-018-6033-3. Epub 2018 Jan 16.
5
Distal pancreatectomy: a single institution's experience in open, laparoscopic, and robotic approaches.
J Am Coll Surg. 2015 Jan;220(1):18-27. doi: 10.1016/j.jamcollsurg.2014.10.004. Epub 2014 Oct 15.
6
Minimally invasive versus open distal pancreatectomy: a matched analysis using ACS-NSQIP.
Surg Endosc. 2023 Jan;37(1):617-623. doi: 10.1007/s00464-022-09363-y. Epub 2022 Jun 15.
7
Laparoscopic versus open distal pancreatectomy: a clinical and cost-effectiveness study.
Surg Endosc. 2012 Jun;26(6):1670-4. doi: 10.1007/s00464-011-2090-6. Epub 2011 Dec 17.
8
[Comparison of short-term clinical outcome between laparoscopic distal pancreatectomy and open distal pancreatectomy].
Zhonghua Zhong Liu Za Zhi. 2020 Jun 23;42(6):495-500. doi: 10.3760/cma.j.cn112152-20190627-00398.
10
Laparoscopic versus open distal pancreatectomy: a single-institution case-control study.
Surg Endosc. 2012 Feb;26(2):402-7. doi: 10.1007/s00464-011-1887-7. Epub 2011 Sep 10.

本文引用的文献

2
The impact of unplanned conversion to an open procedure during minimally invasive pancreatectomy.
J Surg Res. 2018 Jul;227:168-177. doi: 10.1016/j.jss.2018.02.028. Epub 2018 Mar 19.
4
Conversion of Minimally Invasive Distal Pancreatectomy: Predictors and Outcomes.
Ann Surg Oncol. 2017 Nov;24(12):3725-3731. doi: 10.1245/s10434-017-6062-5. Epub 2017 Aug 28.
5
Standardizing terminology for minimally invasive pancreatic resection.
HPB (Oxford). 2017 Mar;19(3):182-189. doi: 10.1016/j.hpb.2017.01.006.
8
Laparoscopic radical 'no-touch' left pancreatosplenectomy for pancreatic ductal adenocarcinoma: technique and results.
Surg Endosc. 2016 Sep;30(9):3830-8. doi: 10.1007/s00464-015-4685-9. Epub 2015 Dec 16.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验