Iwakura Masahiro, Okura Kazuki, Shibata Kazuyuki, Kawagoshi Atsuyoshi, Sugawara Keiyu, Takahashi Hitomi, Shioya Takanobu
Department of Rehabilitation, Akita City Hospital; Department of Physical Therapy, Akita University Graduate School of Health Sciences, Akita, Japan.
Department of Physical Therapy, Akita University Graduate School of Health Sciences, Akita, Japan.
Int J Chron Obstruct Pulmon Dis. 2016 Jul 1;11:1505-14. doi: 10.2147/COPD.S107936. eCollection 2016.
Little is known regarding the relationship between balance impairments and physical activity in COPD. There has been no study investigating the relationship between balance and objectively measured physical activity. Here we investigated the association between balance and physical activity measured by an activity monitor in elderly COPD patients.
Twenty-two outpatients with COPD (mean age, 72±7 years; forced expiratory volume in 1 second, 53%±21% predicted) and 13 age-matched healthy control subjects (mean age, 72±6 years) participated in the study. We assessed all 35 subjects' balance (one-leg standing test [OLST] times, Short Physical Performance Battery total scores, standing balance test scores, 4 m gait speed, and five-times sit-to-stand test [5STST]) and physical activity (daily steps and time spent in moderate-to-vigorous physical activity per day [MV-PA]). Possible confounders were assessed in the COPD group. The between-group differences in balance test scores and physical activity were analyzed. A correlation analysis and multivariate regression analysis were conducted in the COPD group.
The COPD patients exhibited significant reductions in OLST times (P=0.033), Short Physical Performance Battery scores (P=0.013), 4 m gait speed (P<0.001), five-times sit-to-stand times (P=0.002), daily steps (P=0.003), and MV-PA (P=0.022) compared to the controls; the exception was the standing balance test scores. The correlation and multivariate regression analyses revealed significant independent associations between OLST times and daily steps (P<0.001) and between OLST times and MV-PA (P=0.014) in the COPD group after adjusting for possible confounding factors.
Impairments in balance and reductions in physical activity were observed in the COPD group. Deficits in balance are independently associated with physical inactivity.
关于慢性阻塞性肺疾病（COPD）患者平衡功能障碍与身体活动之间的关系，目前所知甚少。尚无研究调查平衡功能与客观测量的身体活动之间的关系。在此，我们调查了老年COPD患者平衡功能与通过活动监测器测量的身体活动之间的关联。
22例COPD门诊患者（平均年龄72±7岁；第1秒用力呼气量为预测值的53%±21%）和13名年龄匹配的健康对照者（平均年龄72±6岁）参与了本研究。我们评估了所有35名受试者的平衡功能（单腿站立试验[OLST]时间、简短体能状况量表总分、站立平衡测试分数、4米步行速度以及五次坐立试验[5STST]）和身体活动（每日步数以及每天进行中度至剧烈身体活动的时间[MV-PA]）。在COPD组中评估了可能的混杂因素。分析了两组在平衡测试分数和身体活动方面的组间差异。在COPD组中进行了相关性分析和多变量回归分析。
与对照组相比，COPD患者的OLST时间（P = 0.033）、简短体能状况量表分数（P = 0.013）、4米步行速度（P < 0.001）、五次坐立时间（P = 0.002）、每日步数（P = 0.003）和MV-PA（P = 0.022）均显著降低；站立平衡测试分数除外。相关性分析和多变量回归分析显示，在调整可能的混杂因素后，COPD组中OLST时间与每日步数之间（P < 0.001）以及OLST时间与MV-PA之间（P = 0.014）存在显著的独立关联。
在COPD组中观察到平衡功能受损和身体活动减少。平衡功能缺陷与身体活动不足独立相关。
