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Early Bronchus-Associated Lymphoid Tissue Lymphoma Diagnosed with Immunoglobulin Heavy Chain Molecular Testing.

作者信息

Li Pen, Cheung Lawrence, Chiu Brian

机构信息

Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3.

Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3; Division of Critical Care Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3.

出版信息

Can Respir J. 2016;2016:7056035. doi: 10.1155/2016/7056035. Epub 2016 Mar 31.

DOI:10.1155/2016/7056035
PMID:27445561
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4904558/
Abstract

When extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue (MALT), a low grade B-cell lymphoma, arises in the lung it is referred to as bronchus-associated lymphoid tissue (BALT) lymphoma. We describe a patient with a history of Sjögren's syndrome and rheumatoid arthritis with dyspnea and imaging consistent with lymphoid interstitial pneumonia (LIP). However, while histology and immunohistochemistry lacked definitive features of a lymphoma, immunoglobulin heavy chain (IgH) polymerase chain reaction testing demonstrated B-cell monoclonality, consistent with an early BALT lymphoma.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46e2/4904558/863af9bc606b/CRJ2016-7056035.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46e2/4904558/6206784aa426/CRJ2016-7056035.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46e2/4904558/863af9bc606b/CRJ2016-7056035.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46e2/4904558/6206784aa426/CRJ2016-7056035.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46e2/4904558/863af9bc606b/CRJ2016-7056035.002.jpg

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本文引用的文献

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Eur Respir J. 2009 Dec;34(6):1408-16. doi: 10.1183/09031936.00039309. Epub 2009 Jun 18.
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