Garcia-Olive Ignasi, Radua Joaquim, Fiz Jose Antonio, Sanz-Santos Jose, Ruiz-Manzano Juan
Respiratory Department, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet, s/n, Badalona, 08916 Barcelona, Spain; Ciber de Enfermedades Respiratorias (CIBERES), Carretera Soller km 12, Bunyola, 07110 Mallorca, Spain; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Carretera del Canyet, s/n, Badalona, 08916 Barcelona, Spain.
Department of Statistics, FIDMAG Research Unit, Sant Boi de Llobregat, 08830 Barcelona, Spain; Ciber de Salud Mental (CIBERSAM), 28035 Madrid, Spain.
Can Respir J. 2016;2016:9242185. doi: 10.1155/2016/9242185. Epub 2016 Mar 7.
Background. The relationship between air pollution and exacerbation of respiratory diseases is well established. Nevertheless, its association with hemoptysis has been poorly investigated. This paper describes the relationship of air pollutants with severe hemoptysis. Methods. All consecutive subjects with severe hemoptysis during a 5-year period were included. The relationship between the contamination measurements and the frequency of embolizations was analyzed using Poisson regressions. In these regressions, the dependent variable was the monthly number of embolizations in a given month and the independent variable was either the concentration of an air contaminant during the same month, the concentration of the air contaminant during the previous month, or the difference between the two. Results. A higher total number of embolizations per month were observed over the months with increases in the concentration of NO. The number of embolizations was 2.0 in the 33 months with no increases in the concentration of NO, 2.1 in the 12 months with small increases, 2.2 in the 5 months with moderate increases, 2.5 in the 4 months with large increases, and 4.0 in the 5 months with very large increases. Conclusion. There is association between hemoptysis and increases in the concentration of atmospheric NO in Badalona (Spain).
背景。空气污染与呼吸系统疾病加重之间的关系已得到充分证实。然而,其与咯血的关联研究较少。本文描述了空气污染物与严重咯血之间的关系。方法。纳入了5年间所有连续的严重咯血患者。使用泊松回归分析污染测量值与栓塞频率之间的关系。在这些回归分析中,因变量是给定月份的每月栓塞次数,自变量是同一月份空气污染物的浓度、前一个月空气污染物的浓度或两者之间的差值。结果。在二氧化氮浓度增加的月份,每月观察到的栓塞总数更高。在二氧化氮浓度无增加的33个月中,栓塞次数为2.0;在小幅增加的12个月中,栓塞次数为2.1;在中度增加的5个月中,栓塞次数为2.2;在大幅增加的4个月中,栓塞次数为2.5;在大幅增加的5个月中,栓塞次数为4.0。结论。在西班牙巴达洛纳,咯血与大气中二氧化氮浓度增加之间存在关联。