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类风湿关节炎特定亚组患者的气质性情感

Dispositional Affect in Unique Subgroups of Patients with Rheumatoid Arthritis.

作者信息

Rice Danielle B, Mehta Swati, Pope Janet E, Harth Manfred, Shapiro Allan, Teasell Robert W

机构信息

Lawson Health Research Institute, London, ON, Canada N6C 0A7; St. Joseph's Health Care, Parkwood Institute, London, ON, Canada N6C 0A7.

Lawson Health Research Institute, London, ON, Canada N6C 0A7; St. Joseph's Health Care, Parkwood Institute, London, ON, Canada N6C 0A7; Western University, London, ON, Canada N6A 3K7.

出版信息

Pain Res Manag. 2016;2016:1024985. doi: 10.1155/2016/1024985. Epub 2016 Mar 3.

DOI:10.1155/2016/1024985
PMID:27445594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4904597/
Abstract

Background. Patients with rheumatoid arthritis may experience increased negative outcomes if they exhibit specific patterns of dispositional affect. Objective. To identify subgroups of patients with rheumatoid arthritis based on dispositional affect. The secondary objective was to compare mood, pain catastrophizing, fear of pain, disability, and quality of life between subgroups. Methods. Outpatients from a rheumatology clinic were categorized into subgroups by a cluster analysis based on dispositional affect. Differences in outcomes were compared between clusters through multivariate analysis of covariance. Results. 227 patients were divided into two subgroups. Cluster 1 (n = 85) included patients reporting significantly higher scores on all dispositional variables (experiential avoidance, anxiety sensitivity, worry, fear of pain, and perfectionism; all p < 0.001) compared to patients in Cluster 2 (n = 142). Patients in Cluster 1 also reported significantly greater mood impairment, pain anxiety sensitivity, and pain catastrophizing (all p < 0.001). Clusters did not differ on quality of life or disability. Conclusions. The present study identifies a subgroup of rheumatoid arthritis patients who score significantly higher on dispositional affect and report increased mood impairment, pain anxiety sensitivity, and pain catastrophizing. Considering dispositional affect within subgroups of patients with RA may help health professionals tailor interventions for the specific stressors that these patients experience.

摘要

背景。类风湿性关节炎患者若表现出特定的性格情绪模式,可能会有更多负面结果。目的。基于性格情绪来识别类风湿性关节炎患者亚组。次要目的是比较各亚组之间的情绪、疼痛灾难化、疼痛恐惧、残疾情况及生活质量。方法。通过基于性格情绪的聚类分析,将风湿病门诊患者分为不同亚组。通过多变量协方差分析比较各亚组之间的结果差异。结果。227名患者被分为两个亚组。与第2组(n = 142)患者相比,第1组(n = 85)患者在所有性格变量(经验性回避、焦虑敏感性、担忧、疼痛恐惧和完美主义;所有p < 0.001)上的得分显著更高。第1组患者还报告有更严重的情绪损伤、疼痛焦虑敏感性和疼痛灾难化(所有p < 0.001)。两组在生活质量或残疾方面无差异。结论。本研究识别出一组类风湿性关节炎患者,他们在性格情绪上得分显著更高,并报告有更严重的情绪损伤、疼痛焦虑敏感性和疼痛灾难化。考虑类风湿性关节炎患者亚组内的性格情绪,可能有助于医护人员针对这些患者所经历的特定压力源制定个性化干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e149/4904597/cffd6fca5d34/PRM2016-1024985.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e149/4904597/cffd6fca5d34/PRM2016-1024985.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e149/4904597/cffd6fca5d34/PRM2016-1024985.001.jpg

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Health-related quality of life in patients with long-standing rheumatoid arthritis in the era of biologics: data from the German biologics register RABBIT.生物制剂时代长期类风湿关节炎患者的健康相关生活质量:来自德国生物制剂注册库RABBIT的数据
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