Ding Ding, Bu Xianmin, Tian Feng
Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Department of Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Oncol Lett. 2016 Aug;12(2):1546-1550. doi: 10.3892/ol.2016.4787. Epub 2016 Jun 28.
Inflammatory myofibroblastic tumor (IMT) is a rare condition of unclear etiology that is commonly observed in the lung but rarely in the pancreas. WHO classified IMT as a potentially malignant or aggressive tumor. In the present report, the case of a 69-year-old male patient with an IMT in the head of the pancreas, who experienced anorexia, nausea and vomiting, is presented. The patient's clinical symptoms were nonspecific, and the imaging findings revealed a hypovascularized pancreatic mass with stenosis of the descending duodenum. The electronic endoscopy findings revealed protruding lesions in the duodenal bulb and the descending duodenum. Biopsies of the mass were conducted with an electronic endoscope, but were not diagnostic. Subsequent duodenopancreatectomy aided in determining a pathological diagnosis of IMT, based on the histology and immunohistochemistry results. The patient experienced a recovery without further incident, as observed during a regular follow-up 3 years later. IMT in the head of the pancreas is rare, particularly in adults. In the present study, an extremely rare case of IMT involving the head of the pancreas in an adult patient is presented, and the therapeutic options for this condition are discussed.
炎性肌纤维母细胞瘤(IMT)是一种病因不明的罕见疾病,常见于肺部,很少发生于胰腺。世界卫生组织将IMT归类为潜在恶性或侵袭性肿瘤。在本报告中,介绍了一名69岁男性胰腺头部IMT患者的病例,该患者出现厌食、恶心和呕吐症状。患者的临床症状不具特异性,影像学检查发现胰腺肿块血供减少,十二指肠降段狭窄。电子内镜检查发现十二指肠球部和十二指肠降段有突出病变。用电子内镜对肿块进行活检,但未明确诊断。随后的十二指肠胰腺切除术根据组织学和免疫组化结果,辅助确定了IMT的病理诊断。3年后定期随访观察到,患者康复且未再出现问题。胰腺头部IMT罕见,尤其是在成人中。在本研究中,呈现了一例极其罕见的成年患者胰腺头部IMT病例,并讨论了该疾病的治疗选择。