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Cost-effectiveness of alternating magnetic resonance imaging and digital mammography screening in BRCA1 and BRCA2 gene mutation carriers.BRCA1 和 BRCA2 基因突变携带者中交替磁共振成像和数字乳房 X 线摄影筛查的成本效益。
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玛丽亚M4:用于乳腺癌检测的超宽带雷达扫描仪原型的临床评估。

MARIA M4: clinical evaluation of a prototype ultrawideband radar scanner for breast cancer detection.

作者信息

Preece Alan W, Craddock Ian, Shere Mike, Jones Lyn, Winton Helen L

机构信息

Bristol University , School of Clinical Sciences, Southwell Street, Bristol BS2 8EJ, United Kingdom.

Bristol University , School of Electrical and Electronic Engineering, Merchant Venturers Building, Woodland Road, Bristol BS8 1UB, United Kingdom.

出版信息

J Med Imaging (Bellingham). 2016 Jul;3(3):033502. doi: 10.1117/1.JMI.3.3.033502. Epub 2016 Jul 20.

DOI:10.1117/1.JMI.3.3.033502
PMID:27446970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4951628/
Abstract

A microwave imaging system has been developed as a clinical diagnostic tool operating in the 3- to 8-GHz region using multistatic data collection. A total of 86 patients recruited from a symptomatic breast care clinic were scanned with a prototype design. The resultant three-dimensional images have been compared "blind" with available ultrasound and mammogram images to determine the detection rate. Images show the location of the strongest signal, and this corresponded in both older and younger women, with sensitivity of [Formula: see text], which was found to be maintained in dense breasts. The pathway from clinical prototype to clinical evaluation is outlined.

摘要

一种微波成像系统已被开发出来,作为一种临床诊断工具,它在3至8吉赫兹频段运行,采用多静态数据采集方式。从一家有症状乳腺护理诊所招募了86名患者,使用原型设计进行了扫描。将所得的三维图像与现有的超声和乳房X光图像进行了“盲法”比较,以确定检测率。图像显示了最强信号的位置,这在老年和年轻女性中都有对应,灵敏度为[公式:见原文],在致密型乳房中也能保持。概述了从临床原型到临床评估的过程。