Bristol Breast Care Centre, Southmead Hospital, Donal Early Way, Bristol, BS10 5NB, United Kingdom.
Thirlestaine Breast Centre, Thirlestaine Road, Cheltenham, GL53 7AP, United Kingdom.
Eur J Radiol. 2019 Jul;116:61-67. doi: 10.1016/j.ejrad.2019.04.017. Epub 2019 Apr 26.
The MARIA breast imaging system is a clinical diagnostic tool that uses a hemispherical array of radiowave antennas to generate three-dimensional images of the internal breast. The system utilises the variance of dielectric contrast within the breast volume in order to identify areas of interest for further diagnostic investigation. This multicentre study of 225 patients was conducted at three trial sites and recruited women with both malignant and benign lesions. The MARIA images from the study were read by both clinicians who had access to the patient's clinical information, as well as by 'blind' reviewers who did not. Results from the study show an overall sensitivity of 76% for the system, which was similar across benign and malignant findings, and in denser breasts. The results from this study are outlined here and discussions on ongoing and future work with MARIA are deliberated.
MARIA 乳房成像系统是一种临床诊断工具，它使用半球形的无线电波天线阵列来生成乳房内部的三维图像。该系统利用乳房体积内介电对比度的变化来识别需要进一步诊断研究的感兴趣区域。这项在三个试验点进行的、共有 225 名患者参与的多中心研究招募了患有良性和恶性病变的女性。该研究的 MARIA 图像由既了解患者临床信息又不了解患者临床信息的临床医生和“盲”审读者进行解读。研究结果显示，该系统的整体敏感性为 76%，在良性和恶性发现以及致密乳房中均相似。本文概述了这项研究的结果，并讨论了正在进行的和未来与 MARIA 相关的工作。
