Glemser Philip A, Pfleiderer Michael, Heger Anna, Tremper Jan, Krauskopf Astrid, Schlemmer Heinz-Peter, Yen Kathrin, Simons David
Institute of Forensic Medicine, University Hospital of Heidelberg, Voßstraße 2, 69115, Heidelberg, Germany.
Department of Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Int J Legal Med. 2017 Mar;131(2):489-496. doi: 10.1007/s00414-016-1412-6. Epub 2016 Jul 22.
The aim of this multi-reader feasibility study was to evaluate new post-processing CT imaging tools in rib fracture assessment of forensic cases by analyzing detection time and diagnostic accuracy.
Thirty autopsy cases (20 with and 10 without rib fractures in autopsy) were randomly selected and included in this study. All cases received a native whole body CT scan prior to the autopsy procedure, which included dissection and careful evaluation of each rib. In addition to standard transverse sections (modality A), CT images were subjected to a reconstruction algorithm to compute axial labelling of the ribs (modality B) as well as "unfolding" visualizations of the rib cage (modality C, "eagle tool"). Three radiologists with different clinical and forensic experience who were blinded to autopsy results evaluated all cases in a random manner of modality and case.
Rib fracture assessment of each reader was evaluated compared to autopsy and a CT consensus read as radiologic reference. A detailed evaluation of relevant test parameters revealed a better accordance to the CT consensus read as to the autopsy. Modality C was the significantly quickest rib fracture detection modality despite slightly reduced statistic test parameters compared to modalities A and B.
Modern CT post-processing software is able to shorten reading time and to increase sensitivity and specificity compared to standard autopsy alone. The eagle tool as an easy to use tool is suited for an initial rib fracture screening prior to autopsy and can therefore be beneficial for forensic pathologists.
这项多阅片者可行性研究的目的是通过分析检测时间和诊断准确性,评估用于法医案件肋骨骨折评估的新型CT后处理成像工具。
随机选取30例尸检病例(尸检中有20例有肋骨骨折,10例无肋骨骨折)纳入本研究。所有病例在尸检程序之前均接受了一次全身CT平扫,尸检程序包括对每根肋骨进行解剖和仔细评估。除了标准横断面(模式A)外,CT图像还采用一种重建算法来计算肋骨的轴向标记(模式B)以及胸廓的“展开”可视化图像(模式C,“鹰工具”)。三名对尸检结果不知情的、具有不同临床和法医经验的放射科医生以随机的模式和病例顺序对所有病例进行评估。
将每位阅片者对肋骨骨折的评估结果与尸检结果以及作为放射学参考的CT一致性解读结果进行比较。对相关测试参数的详细评估显示,与尸检结果相比,与CT一致性解读结果的符合度更高。尽管与模式A和B相比,模式C的统计测试参数略有降低,但它是明显最快的肋骨骨折检测模式。
与单独的标准尸检相比,现代CT后处理软件能够缩短阅片时间,并提高敏感性和特异性。“鹰工具”作为一种易于使用的工具,适用于尸检前的初步肋骨骨折筛查,因此对法医病理学家可能有益。