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对于阻塞性睡眠呼吸暂停的治疗,口鼻面罩比鼻罩和鼻枕面罩需要更高的压力。

Oronasal Masks Require a Higher Pressure than Nasal and Nasal Pillow Masks for the Treatment of Obstructive Sleep Apnea.

作者信息

Deshpande Sheetal, Joosten Simon, Turton Anthony, Edwards Bradley A, Landry Shane, Mansfield Darren R, Hamilton Garun S

机构信息

Department of Lung and Sleep Medicine, Monash Health, Victoria, Australia.

School of Clinical Sciences, Monash University, Victoria, Australia.

出版信息

J Clin Sleep Med. 2016 Sep 15;12(9):1263-8. doi: 10.5664/jcsm.6128.

Abstract

STUDY OBJECTIVES

Oronasal masks are frequently used for continuous positive airway pressure (CPAP) treatment in patients with obstructive sleep apnea (OSA). The aim of this study was to (1) determine if CPAP requirements are higher for oronasal masks compared to nasal mask interfaces and (2) assess whether polysomnography and patient characteristics differed among mask preference groups.

METHODS

Retrospective analysis of all CPAP implementation polysomnograms between July 2013 and June 2014. Prescribed CPAP level, polysomnography results and patient data were compared according to mask type (n = 358).

RESULTS

Oronasal masks were used in 46%, nasal masks in 35% and nasal pillow masks in 19%. There was no difference according to mask type for baseline apnea-hypopnea index (AHI), body mass index (BMI), waist or neck circumference. CPAP level was higher for oronasal masks, 12 (10-15.5) cm H2O compared to nasal pillow masks, 11 (8-12.5) cm H2O and nasal masks, 10 (8-12) cm H2O, p < 0.0001 (Median [interquartile range]). Oronasal mask type, AHI, age, and BMI were independent predictors of a higher CPAP pressure (p < 0.0005, adjusted R(2) = 0.26.). For patients with CPAP ≥ 15 cm H2O, there was an odds ratio of 4.5 (95% CI 2.5-8.0) for having an oronasal compared to a nasal or nasal pillow mask. Residual median AHI was higher for oronasal masks (11.3 events/h) than for nasal masks (6.4 events/h) and nasal pillows (6.7 events/h), p < 0.001.

CONCLUSIONS

Compared to nasal mask types, oronasal masks are associated with higher CPAP pressures (particularly pressures ≥ 15 cm H2O) and a higher residual AHI. Further evaluation with a randomized control trial is required to definitively establish the effect of mask type on pressure requirements.

COMMENTARY

A commentary on this article appears in this issue on page 1209.

摘要

研究目的

口鼻面罩常用于阻塞性睡眠呼吸暂停(OSA)患者的持续气道正压通气(CPAP)治疗。本研究的目的是:(1)确定与鼻面罩接口相比,口鼻面罩的CPAP需求是否更高;(2)评估多导睡眠图和患者特征在面罩偏好组之间是否存在差异。

方法

对2013年7月至2014年6月期间所有CPAP实施的多导睡眠图进行回顾性分析。根据面罩类型(n = 358)比较规定的CPAP水平、多导睡眠图结果和患者数据。

结果

46%的患者使用口鼻面罩,35%使用鼻面罩,19%使用鼻枕面罩。根据面罩类型,基线呼吸暂停低通气指数(AHI)、体重指数(BMI)、腰围或颈围无差异。口鼻面罩的CPAP水平更高,为12(10 - 15.5)cm H2O,而鼻枕面罩为11(8 - 12.5)cm H2O,鼻面罩为10(8 - 12)cm H2O,p < 0.0001(中位数[四分位间距])。口鼻面罩类型、AHI、年龄和BMI是较高CPAP压力的独立预测因素(p < 0.0005,调整后R(2) = 0.26)。对于CPAP≥15 cm H2O的患者,使用口鼻面罩与使用鼻面罩或鼻枕面罩相比,比值比为4.5(95%可信区间2.5 - 8.0)。口鼻面罩的残余中位数AHI(11.3次/小时)高于鼻面罩(6.4次/小时)和鼻枕(6.7次/小时),p < 0.001。

结论

与鼻面罩类型相比,口鼻面罩与更高的CPAP压力(特别是压力≥15 cm H2O)和更高的残余AHI相关。需要通过随机对照试验进行进一步评估,以明确确定面罩类型对压力需求的影响。

评论

关于本文的一篇评论发表在本期第1209页。

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