Ebben Matthew R, Milrad Sara, Dyke Jonathan P, Phillips C Douglas, Krieger Ana C
Department of Neurology, Weill Cornell Medical College, New York, NY, USA.
Center for Sleep Medicine, Weill Cornell Medical College, 425 East 61st Street, 5th Floor, New York, NY, 10065, USA.
Sleep Breath. 2016 Mar;20(1):79-85. doi: 10.1007/s11325-015-1187-x. Epub 2015 Apr 30.
It is known that oronasal masks are not as effective at opening the upper airway compared to nasal only continuous positive airway pressure (CPAP) masks in patients with sleep-disordered breathing. However, the physiological mechanism for this difference in efficacy is not known; although, it has been hypothesized to involve the retroglossal and/or retropalatal region of the upper airway. The objective of this study was to investigate differences in retroglossal and retropalatal anterior-posterior space with the use of oronasal vs. nasal CPAP masks using real-time cine magnetic resonance imaging (cMRI).
Ten subjects (eight men, two women) with obstructive sleep apnea (OSA) were given cMRI with both nasal and oronasal CPAP masks. Each subject was imaged with each interface at pressures of 5, 10, and 15 cm of H2O, while in the supine position along the sagittal plane.
The oronasal mask produced significantly less airway opening in the retropalatal region of the upper airway compared to the nasal mask interface. During exhalation, mask style had a significant effect on anterior-posterior distance p = 0.016. No differences were found in the retroglossal region between mask styles.
Our study confirmed previous findings showing differences in treatment efficacy between oronasal and nasal mask styles. We have shown anatomic evidence that the nasal mask is more effective in opening the upper airway compared to the oronasal mask in the retropalatal region.
众所周知,在睡眠呼吸障碍患者中,口鼻面罩在打开上气道方面不如仅使用鼻持续气道正压通气(CPAP)面罩有效。然而,这种疗效差异的生理机制尚不清楚;尽管有人推测这涉及上气道的舌后和/或腭后区域。本研究的目的是使用实时电影磁共振成像(cMRI)研究使用口鼻面罩与鼻CPAP面罩时舌后和腭后前后间隙的差异。
对10名患有阻塞性睡眠呼吸暂停(OSA)的受试者(8名男性,2名女性)使用鼻和口鼻CPAP面罩进行cMRI检查。每个受试者在5、10和15厘米水柱的压力下,仰卧位沿矢状面,用每种接口进行成像。
与鼻面罩接口相比,口鼻面罩在上气道腭后区域产生的气道开口明显较小。呼气时,面罩类型对前后距离有显著影响,p = 0.016。面罩类型在舌后区域未发现差异。
我们的研究证实了先前的发现,即口鼻面罩和鼻面罩类型在治疗效果上存在差异。我们已经证明了解剖学证据,即与口鼻面罩相比,鼻面罩在打开腭后区域的上气道方面更有效。