新生儿死亡：免疫接种安全性数据的病例定义及数据收集、分析与呈现指南。
Neonatal death: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data.
作者信息
Pathirana Jayani, Muñoz Flor M, Abbing-Karahagopian Victoria, Bhat Niranjan, Harris Tara, Kapoor Ambujam, Keene Daniel L, Mangili Alexandra, Padula Michael A, Pande Stephen L, Pool Vitali, Pourmalek Farshad, Varricchio Frederick, Kochhar Sonali, Cutland Clare L
机构信息
Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, Johannesburg, South Africa; Department of Science and Technology, National Research Foundation, Vaccine Preventable Diseases, South Africa; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Departments of Pediatrics, Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
出版信息
Vaccine. 2016 Dec 1;34(49):6027-6037. doi: 10.1016/j.vaccine.2016.03.040. Epub 2016 Jul 19.
More than 40% of all deaths in children under 5 years of age occur during the neonatal period: the first month of life. Immunization of pregnant women has proven beneficial to both mother and infant by decreasing morbidity and mortality. With an increasing number of immunization trials being conducted in pregnant women, as well as roll-out of recommended vaccines to pregnant women, there is a need to clarify details of a neonatal death. This manuscript defines levels of certainty of a neonatal death, related to the viability of the neonate, who confirmed the death, and the timing of the death during the neonatal period and in relation to immunization of the mother.
5岁以下儿童中超过40%的死亡发生在新生儿期，即生命的第一个月。事实证明，孕妇接种疫苗对母亲和婴儿均有益，可降低发病率和死亡率。随着针对孕妇开展的免疫试验越来越多，以及向孕妇推广推荐疫苗，有必要明确新生儿死亡的细节。本手稿定义了新生儿死亡的确信程度，这与新生儿的生存能力、确认死亡的人员以及新生儿期内的死亡时间以及与母亲免疫接种的关系有关。
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