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腹膜后腹腔镜根治性肾切除术气腹最后一分钟时二氧化碳储存量与腹膜后腔隙面积的相关性

Correlation between CO2 storage at the last minute of gas insufflation and area of retroperitoneal lacuna during retroperitoneal laparoscopic radical nephrectomy.

作者信息

Hu Jian-Jun, Liu Ya-Hua, Yu Chan-Juan, Jialielihan Nuerbolati

机构信息

Anesthesia Department of Xinjiang Medical University Affiliated Tumor Hospital, No. 789, Suzhoudong Road, Urumqi, 830011, Xinjiang, China.

出版信息

BMC Anesthesiol. 2016 Jul 22;16(1):42. doi: 10.1186/s12871-016-0208-z.

Abstract

BACKGROUND

Adequate operation interspace is the premise of laparoscopy, and carbon dioxide (CO2) was an ideal gas for forming lacuna. A retroperitoneal space is used to form operation interspace in retroperitoneal laparoscopic radical nephrectomy by making ballooning, and the retroperitoneal space has no relative complete and airtight serous membrane, therefore CO2 absorption may be greater in retroperitoneal than transperitoneal laparoscopic radical nephrectomy. Excess CO2 absorption may induce hypercapnemia and further cause physiopathological change of respiratory and circulatory system. Therefore, exact evaluation of amount of CO2 which is eliminated from body via minute ventilation is important during retroperitoneal laparoscopic radical nephrectomy. The aim of the paper is to study the correlation between CO2 storage at the last minute of gas insufflation and area of retroperitoneal lacuna during retroperitoneal laparoscopic radical nephrectomy.

METHODS

Forty ASA I/II patients undergoing retroperitoneal laparoscopic radical nephrectomy were enrolled. CO2 storage at the last minute of gas insufflation and area of a retroperitoneal lacuna were observed. Linear correlation and regression were performed to determine the correlation between them.

RESULTS

There was positive correlation between CO2 storage at the last minute of gas insufflation and area of retroperitoneal lacuna (r = 0.880, P = 0.000), and the equation of linear regression was y = -83.097 + 0.925x (R(2) = 0.780, t = 11.610, P = 0.000).

CONCLUSIONS

Amount of CO2 which is eliminated from body via mechanical ventilation could be calculated by measuring the area of retroperitoneal lacuna during retroperitoneal laparoscopic radical nephrectomy, and an anesthetist should be aware of the size of lacuna to predict high CO2 storage at the last minute of gas insufflation.

摘要

背景

充足的手术操作空间是腹腔镜手术的前提,二氧化碳(CO₂)是形成腔隙的理想气体。在腹膜后腹腔镜根治性肾切除术中,通过建立气腹来利用腹膜后间隙形成手术操作空间,且腹膜后间隙没有相对完整且密闭的浆膜,因此与经腹腹腔镜根治性肾切除术相比,腹膜后腹腔镜根治性肾切除术中CO₂的吸收可能更多。过多的CO₂吸收可能诱发高碳酸血症,并进一步导致呼吸和循环系统的生理病理改变。因此,在腹膜后腹腔镜根治性肾切除术中,准确评估通过分钟通气量从体内排出的CO₂量非常重要。本文旨在研究腹膜后腹腔镜根治性肾切除术中气腹最后一分钟时CO₂蓄积量与腹膜后腔隙面积之间的相关性。

方法

纳入40例接受腹膜后腹腔镜根治性肾切除术的美国麻醉医师协会(ASA)I/II级患者。观察气腹最后一分钟时的CO₂蓄积量和腹膜后腔隙面积。进行线性相关和回归分析以确定两者之间的相关性。

结果

气腹最后一分钟时的CO₂蓄积量与腹膜后腔隙面积呈正相关(r = 0.880,P = 0.000),线性回归方程为y = -83.097 + 0.925x(R² = 0.780,t = 11.610,P = 0.000)。

结论

在腹膜后腹腔镜根治性肾切除术中,通过测量腹膜后腔隙面积可计算出通过机械通气从体内排出的CO₂量,麻醉医师应了解腔隙大小,以预测气腹最后一分钟时的高CO₂蓄积量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abdf/4957877/12356855b630/12871_2016_208_Fig1_HTML.jpg

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