Alnawaiseh Maged, Schubert Friederike, Nelis Pieter, Wirths Gabriele, Rosentreter André, Eter Nicole
Department of Ophthalmology, University of Muenster Medical Center, Albert-Schweitzer-Campus 1, Building D15, 48149, Muenster, Germany.
Department of Ophthalmology, University of Würzburg, Würzburg, Germany.
BMC Ophthalmol. 2016 Jul 22;16:120. doi: 10.1186/s12886-016-0293-2.
Optical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial macroaneurysms (RAMs).
Three eyes of three patients with RAMs were retrospectively included. Fundus photography, OCT, fluorescein angiography (FA), and OCT angiography were performed. The entire imaging data was analyzed in detail.
OCT angiography could detect the RAMs noninvasively without dye injection. By simultaneously observing the OCT scans, it was possible to determine the depth of the RAMs in the retina, to detect the exact localization in relation to the main vessel, and to determine the level of blood flow in the RAMs.
OCT angiography can clearly visualize RAMs without use of a dye. It also allows layer-specific observation of blood flow in each layer of the RAM. OCT angiography provides additional dynamic information on RAMs, which is not obtained with FA and facilitates a better understanding of its morphology and activity. This information in combination with ICG and fluorescein angiography can help to optimize direct laser treatment.
光学相干断层扫描血管造影术是一种新型成像技术,可在无需注射染料的情况下对视网膜和脉络膜血管系统进行无创的体内可视化。本研究的目的是描述视网膜动脉大动脉瘤(RAMs)患者的光学相干断层扫描(OCT)血管造影结果。
回顾性纳入3例患有RAMs的患者的3只眼。进行了眼底照相、OCT、荧光素血管造影(FA)和OCT血管造影。对整个成像数据进行了详细分析。
OCT血管造影无需注射染料即可无创检测RAMs。通过同时观察OCT扫描,能够确定RAMs在视网膜中的深度,检测其相对于主要血管的确切位置,并确定RAMs中的血流水平。
OCT血管造影无需使用染料即可清晰显示RAMs。它还允许对RAMs各层的血流进行分层观察。OCT血管造影提供了关于RAMs的额外动态信息,这是FA无法获得的,有助于更好地理解其形态和活性。这些信息与吲哚菁绿和荧光素血管造影相结合,有助于优化直接激光治疗。