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使用自体骨移植的增强锁定钢板治疗逆行髓内钉固定失败后的股骨远端骨不连。

Augmentative locking plate with autologous bone grafting for distal femoral nonunion subsequent to failed retrograde intramedullary nailing.

作者信息

Ru Jiang-Ying, Cong Yu, Shi Dai, Lu Yang-Hu, Niu Yun-Fei, Xu Hai-Dong

机构信息

Department of Orthopaedics, The First People's Hospital of Yangzhou City, The Second Clinical School of Yangzhou University, Yangzhou 225000, Jiangsu province, People's Republic of China.

Department of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, People's Republic of China.

出版信息

Acta Orthop Traumatol Turc. 2016 Aug;50(4):393-9. doi: 10.1016/j.aott.2016.05.002. Epub 2016 Jun 3.

Abstract

OBJECTIVE

To explore the indications and efficacy of augmentative locking compression plate (LCP) or less invasive stabilization system (LISS)with autogenous bone grafting (BG) in treating distal femoral nonunion subsequent to failed retrograde intramedullary nailing (RIN).

METHODS

A retrospective study was performed for 21 patients with distal femoral nonunion subsequent to failed RIN, who received therapy with either augmentative LCP (n = 11) or LISS with autogenous BG (n = 13). Operation time, time to union, union rate, time to renonunion, complication rate and SF-36 scores a year after hardware removal were compared between the two groups.

RESULTS

The bone union occurred in 13/13 (100%) cases in augmentative LISS group versus 9/11 (81.8%) cases in augmentative LCP group [odds ratio (OR) = 3.21, 95% confidence interval (CI) 0.7-13]. Time to union, time to renonunion, complication rate of the augmentative LCP group were significantly more than that of the augmentative LISS with autogenous BG group (p = 0.023, p = 0.021 and p = 0.033). No significant difference was found in the average operation time of two groups (p = 0.121). At the follow-up a year after hardware removal, statistically significant HRQOL improvement in the augmentive LISS group was measured at the level of pain (p = 0.003) and general health perception (p = 0.011), as compared to the augmentive LCP group.

CONCLUSIONS

We suggest augmentative LCP, for distal femoral nonunios after RIN, may be optimal for that of typeAO33A fractures, whereas augmentative LISS for that of typeAO33C fractures more.

摘要

目的

探讨增强型锁定加压钢板(LCP)或微创稳定系统(LISS)联合自体骨移植(BG)治疗逆行髓内钉(RIN)失败后股骨远端骨不连的适应证及疗效。

方法

对21例RIN失败后股骨远端骨不连患者进行回顾性研究,其中11例采用增强型LCP治疗,13例采用LISS联合自体BG治疗。比较两组的手术时间、骨愈合时间、愈合率、再次骨不连时间、并发症发生率以及取出内固定物后1年的SF-36评分。

结果

增强型LISS组13/13(100%)例实现骨愈合,增强型LCP组9/11(81.8%)例实现骨愈合[优势比(OR)=3.21,95%置信区间(CI)0.7-13]。增强型LCP组的骨愈合时间、再次骨不连时间、并发症发生率均显著高于增强型LISS联合自体BG组(p=0.023、p=0.021和p=0.033)。两组平均手术时间差异无统计学意义(p=0.121)。取出内固定物后1年随访时,与增强型LCP组相比,增强型LISS组在疼痛(p=0.003)和总体健康感知(p=0.011)方面的健康相关生活质量(HRQOL)改善具有统计学意义。

结论

我们建议,对于RIN术后股骨远端骨不连,增强型LCP可能最适用于AO33A骨折类型,而增强型LISS更适用于AO33C骨折类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d5/6197441/1a5d28bcf730/gr1.jpg

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