Wilson Andrew R, Hashibe Mia, Bodson Julia, Gren Lisa H, Taylor Brooke A, Greenwood Jessica, Jackson Brian R, She Rosemary, Egger Marlene J, Kepka Deanna
University of Utah, College of Nursing, 10 South 2000 East, Room 2200, Salt Lake City, Utah, 84112, USA.
Huntsman Cancer Institute, Cancer Control and Population Sciences, 2000 Circle of Hope, Salt Lake City, Utah, 84112, USA.
BMC Womens Health. 2016 Jul 22;16:41. doi: 10.1186/s12905-016-0323-5.
To assess the demographic and attitudinal factors associated with HPV vaccine initiation and completion among 18-26 year old women in Utah.
Between January 2013 and December 2013, we surveyed 325 women from the University of Utah Community Clinics about their HPV vaccine related beliefs and behaviors. Odds ratios (ORs) were estimated from logistic regression models to identify variables related to HPV vaccine initiation and series completion.
Of the 325 participants, 204 (62.8 %) had initiated the vaccine and 159 (48.9 %) had completed the 3-dose series. The variables associated with HPV vaccine initiation were lower age (OR = 1.18 per year); being unmarried (OR = 3.62); not practicing organized religion (OR = 2.40); knowing how HPV spreads (OR = 6.29); knowing the connection between HPV and cervical cancer (OR = 3.90); a belief in the importance of preventive vaccination (OR = 2.45 per scale unit); strength of doctor recommendation (OR = 1.86 per scale unit); and whether a doctor's recommendation was influential (OR = 1.70 per scale unit). These variables were also significantly associated with HPV vaccine completion.
The implications of these findings may help inform policies and interventions focused on increasing HPV vaccination rates among young women. For example, without this information, programs might focus on HPV awareness; however, the results of this study illustrate that awareness is already high (near saturation) in target populations and other factors, such as strong and consistent physician recommendations, are more pivotal in increasing likelihood of vaccination. Additionally, our findings indicate the need for discussions of risk assessment be tailored to the young adult population.
评估犹他州18 - 26岁女性中与HPV疫苗接种起始及完成相关的人口统计学和态度因素。
在2013年1月至2013年12月期间，我们对犹他大学社区诊所的325名女性进行了调查，询问她们与HPV疫苗相关的信念和行为。通过逻辑回归模型估计比值比（OR），以确定与HPV疫苗接种起始及完成系列相关的变量。
在325名参与者中，204人（62.8%）已开始接种疫苗，159人（48.9%）已完成3剂次接种系列。与HPV疫苗接种起始相关的变量包括年龄较小（每年OR = 1.18）；未婚（OR = 3.62）；不参加有组织的宗教活动（OR = 2.40）；了解HPV传播方式（OR = 6.29）；了解HPV与宫颈癌的关联（OR = 3.90）；相信预防性疫苗接种的重要性（每个量表单位OR = 2.45）；医生推荐的力度（每个量表单位OR = 1.86）；以及医生的推荐是否有影响力（每个量表单位OR = 1.70）。这些变量也与HPV疫苗接种完成显著相关。
这些发现的意义可能有助于为旨在提高年轻女性HPV疫苗接种率的政策和干预措施提供信息。例如，如果没有这些信息，项目可能会侧重于提高对HPV的认识；然而，本研究结果表明，目标人群中对HPV的认识已经很高（接近饱和），而其他因素，如医生强烈且一致的推荐，在增加接种可能性方面更为关键。此外，我们的研究结果表明，需要针对年轻成年人群体进行风险评估的讨论。
