Asare Matthew, Agyei-Baffour Peter, Koranteng Adofo, Commeh Mary E, Fosu Emmanuel Sarfo, Elizondo Anjelica, Sturdivant Rodney X
Department of Public Health, Robbins College of Health and Human Sciences, Baylor University, Waco, TX 76798, USA.
School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi P.O. Box UPO-1279, Ghana.
Vaccines (Basel). 2023 Apr 24;11(5):890. doi: 10.3390/vaccines11050890.
The study examined whether the 3R (reframe, prioritize, and reform) communication model intervention can impact parents' and adolescents' HPV vaccination acceptability. We used face-to-face methods to recruit participants from three local churches in the Ashanti Region of Ghana. Participants completed pre- and post-intervention assessments based on the validated Theory of Planned Behavior survey. We organized two face-to-face presentations for parents and adolescents separately for parents ( = 85) and adolescents ( = 85). Participants' post-intervention vs. pre-intervention scores for attitude (mean = 35.46 ± SD = 5.46 vs. mean = 23.42 ± SD = 8.63), knowledge (M = 28.48 ± SD = 5.14 vs. M = 16.56 ± SD = 7.19), confidence (M = 8.96 ± SD = 3.43 vs. M = 6.17 ± SD = 2.84), and intention for vaccine acceptance (M = 4.73 ± SD = 1.78 vs. M = 3.29 ± SD = 1.87) increased significantly ( < 0.001). The intervention showed that for every one-unit increase in the participants' self-confidence and attitude scores, the odds of the HPV vaccination acceptability increased by 22% (95% CI: 10-36) and 6% (95% CI: 0.1-12), respectively. Intention for vaccine acceptance, F (1167) = 6.89, and attitude toward vaccination, F (1167) = 19.87, were significantly higher among parents than adolescents ( < 0.001), after controlling for the baseline scores. These findings suggest that the intervention targeting parents' and adolescents' attitudes and knowledge has the potential to increase HPV vaccination acceptance in Ghana.
该研究调查了3R（重新构建、优先排序和改革）沟通模式干预是否会影响父母和青少年对人乳头瘤病毒（HPV）疫苗接种的接受度。我们采用面对面的方法，从加纳阿散蒂地区的三个当地教会招募参与者。参与者根据经过验证的计划行为理论调查完成干预前和干预后的评估。我们分别为父母（n = 85）和青少年（n = 85）组织了两场面对面的讲座。参与者干预后的态度得分（均值 = 35.46 ± 标准差 = 5.46，干预前均值 = 23.42 ± 标准差 = 8.63）、知识得分（均值 = 28.48 ± 标准差 = 5.14，干预前均值 = 16.56 ± 标准差 = 7.19）、信心得分（均值 = 8.96 ± 标准差 = 3.43，干预前均值 = 6.17 ± 标准差 = 2.84）以及疫苗接种接受意愿得分（均值 = 4.73 ± 标准差 = 1.78，干预前均值 = 3.29 ± 标准差 = 1.87）均显著提高（p < 0.001）。干预结果表明，参与者的自信得分和态度得分每增加一个单位，HPV疫苗接种接受度的几率分别增加22%（95%置信区间：10 - 36）和6%（95%置信区间：0.1 - 12）。在控制基线得分后，父母的疫苗接种接受意愿（F(1,167) = 6.89）和对疫苗接种的态度（F(1,167) = 19.87）显著高于青少年（p < 0.001）。这些发现表明，针对父母和青少年态度及知识的干预措施有可能提高加纳的HPV疫苗接种接受度。
