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对一名患有与单纯疱疹性脑炎相关的盖综合征儿童进行阿昔洛韦延长治疗。

Prolonged acyclovir treatment in a child with opercular syndrome related to herpes simplex encephalitis.

作者信息

Karli Arzu, Şensoy Gülnar, Tekin Emine, Sofuoğlu Ayşe I, Bilgici Meltem C, Özyürek Hamit

机构信息

Division of Child Infectious Diseases, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey.

Division of Child Neurology, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey.

出版信息

J Infect Public Health. 2017 Mar-Apr;10(2):232-234. doi: 10.1016/j.jiph.2016.06.010. Epub 2016 Jul 21.

DOI:10.1016/j.jiph.2016.06.010
PMID:27452287
Abstract

HSV 1 encephalitis is the most common cause of sporadic and focal viral encephalitis. Opercular syndrome is characterized by swallowing and speech difficulties which are associated with deterioration of voluntary control of face, pharynx, tongue and chewing muscles. It can be developed in patients with Herpes simplex encephalitis (HSE). Here, a twelve-year-old boy who was diagnosed with HSE and Opercular syndrome, is presented. The patient recovered without sequela as a result of 30 days of intravenous and 10 days of oral acyclovir treatment. It might be important as well, to personalize and elongate the treatment in terms of prognosis.

摘要

单纯疱疹病毒1型脑炎是散发性局灶性病毒性脑炎最常见的病因。岛盖综合征的特征是吞咽和言语困难,这与面部、咽部、舌头和咀嚼肌自主控制能力的下降有关。它可发生于单纯疱疹性脑炎(HSE)患者。本文介绍了一名被诊断为HSE和岛盖综合征的12岁男孩。经过30天的静脉注射和10天的口服阿昔洛韦治疗,该患者康复且无后遗症。就预后而言,个性化并延长治疗时间可能也很重要。

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