Lambertini F, Catellani D, Vindigni M, Suman M
Advanced Laboratory Research, Barilla G. R. F.lli SpA, via Mantova 166, 43122, Parma, Italy.
J Mass Spectrom. 2016 Sep;51(9):805-13. doi: 10.1002/jms.3815.
Plasticizers may migrate from polyvinyl chloride (PVC) gaskets into the foodstuffs mainly by direct contact during the packaging and sterilization procedure, but also by means of occasional contacts occurring during shipment and storage. The present work reports a reliable liquid chromatography-mass spectrometry (LC-MS) method able to quantify the main plasticizers used in the PVC closure gaskets for metal lids to verify their compliance in both food contact materials and foodstuffs. The atmospheric pressure chemical ionization in the positive ion mode resulted the best performing interface for the multiresidual detection of the plasticizers taken into account, followed by selected/multiple reaction monitoring, selected ion monitoring or full scan experiments, depending on the compounds to detect. The method was single-laboratory validated, demonstrating to reach a good sensitivity, thus making possible to perform analysis without any preliminary sample purification or concentration step. It proved to be effectively applicable not only for the determination of plasticizers in PVC gaskets but also in complex food matrices. In particular, it was applied for monitoring plasticizer migration into sauces placed in contact with the lids in worst storage conditions, observing therefore their trend during the shelf-life. Copyright © 2016 John Wiley & Sons, Ltd.
增塑剂可能会在包装和灭菌过程中通过直接接触，也会在运输和储存期间偶尔接触的方式，从聚氯乙烯（PVC）垫圈迁移到食品中。本研究报告了一种可靠的液相色谱 - 质谱（LC-MS）方法，该方法能够对金属盖PVC密封垫圈中使用的主要增塑剂进行定量，以验证它们在食品接触材料和食品中的合规性。对于所考虑的增塑剂的多残留检测，正离子模式下的大气压化学电离是性能最佳的接口，随后根据要检测的化合物进行选择/多反应监测、选择离子监测或全扫描实验。该方法在单一实验室得到验证，证明具有良好的灵敏度，因此无需任何初步的样品净化或浓缩步骤即可进行分析。事实证明，它不仅有效地适用于测定PVC垫圈中的增塑剂，也适用于复杂的食品基质。特别是，它被用于监测增塑剂在最恶劣储存条件下迁移到与盖子接触的调味汁中的情况，从而观察它们在保质期内的变化趋势。版权所有© 2016约翰威立父子有限公司。
