Vygen Sabine, Tiffany Amanda, Rull Monica, Ventura Alexandre, Wolz Anja, Jambai Amara, Porten Klaudia
French Institute of Public Health Surveillance, Alerts and Regions Coordination Department, Regional office in Aquitaine, Bordeaux, France. European Program for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden. Robert Koch-Institut, Berlin, Germany.
Epicentre, Geneva, Switzerland.
Am J Trop Med Hyg. 2016 Oct 5;95(4):897-901. doi: 10.4269/ajtmh.16-0295. Epub 2016 Jul 25.
Little is known about the residual effects of the west African Ebola virus disease (Ebola) epidemic on non-Ebola mortality and health-seeking behavior in Sierra Leone. We conducted a retrospective household survey to estimate mortality and describe health-seeking behavior in Western Area, Sierra Leone, between May 25, 2014, and February 16, 2015. We used two-stage cluster sampling, selected 30 geographical sectors with probability proportional to population size, and sampled 30 households per sector. Survey teams conducted face-to-face interviews and collected information on mortality and health-seeking behavior. We calculated all-cause and Ebola-specific mortality rates and compared health-seeking behavior before and during the Ebola epidemic using χ and Fisher's exact tests. Ninety-six deaths, 39 due to Ebola, were reported in 898 households. All-cause and Ebola-specific mortality rates were 0.52 (95% confidence interval [CI] = 0.29-0.76) and 0.19 (95% CI = 0.01-0.38) per 10,000 inhabitants per day, respectively. Of those households that reported a sick family member during the month before the survey, 86% (73/85) sought care at a health facility before the epidemic, compared with 58% (50/86) in February 2015 (P = 0.013). Reported self-medication increased from 4% (3/85) before the epidemic to 23% (20/86) during the epidemic (P = 0.013). Underutilization of health services and increased self-medication did not show a demonstrable effect on non-Ebola-related mortality. Nevertheless, the residual effects of outbreaks need to be taken into account for the future. Recovery efforts should focus on rebuilding both the formalized health system and the population's trust in it.
关于西非埃博拉病毒病(埃博拉)疫情对塞拉利昂非埃博拉死亡率及就医行为的残留影响,人们了解甚少。我们开展了一项回顾性家庭调查,以估算2014年5月25日至2015年2月16日期间塞拉利昂西部地区的死亡率,并描述就医行为。我们采用两阶段整群抽样法,按人口规模比例选取了30个地理区域,每个区域抽取30户家庭。调查团队进行面对面访谈,收集死亡率及就医行为方面的信息。我们计算了全死因死亡率和埃博拉特异性死亡率,并使用χ检验和费舍尔精确检验比较了埃博拉疫情之前和期间的就医行为。在898户家庭中报告了96例死亡,其中39例死于埃博拉。全死因死亡率和埃博拉特异性死亡率分别为每10,000居民每天0.52(95%置信区间[CI]=0.29 - 0.76)和0.19(95%CI = 0.01 - 0.38)。在调查前一个月报告有家庭成员患病的家庭中,86%(73/85)在疫情之前会前往医疗机构就医,而在2015年2月这一比例为58%(50/86)(P = 0.013)。报告的自我药疗比例从疫情之前的4%(3/85)增至疫情期间的23%(20/86)(P = 0.013)。卫生服务利用不足和自我药疗增加对非埃博拉相关死亡率未显示出明显影响。尽管如此,未来仍需考虑疫情的残留影响。恢复工作应侧重于重建正规卫生系统以及民众对该系统的信任。