Paediatric Urology, Hospital General Universitario Gregorio Marañón , Madrid , Spain.
Front Pediatr. 2016 Jul 8;4:72. doi: 10.3389/fped.2016.00072. eCollection 2016.
The aim of this study is to analyze results of retrograde endopyelotomy with cutting balloon for treatment of ureteropelvic junction obstruction (UPJO) in infants.
We routinely treat patients with UPJO under 18 months of age with retrograde high-pressure balloon dilatation of the pelviureteric junction (PUJ). During the procedure, in these cases where narrowing at the PUJ persists, endopyelotomy with cutting balloon is performed. Endopyelotomy is performed over guidewire with 5-mm Cutting Balloon™ under fluoroscopic control. Double-J stents is left in situ for 4 weeks. We retrospectively analyzed the postoperative, clinical, and radiological outcome infants treated with cutting balloon endopyelotomy between 2007 and 2015.
Sixteen patients required cutting balloon endopyelotomy to achieve complete resolution of narrowing of the waist observed during high-pressure balloon dilatation of the PUJ. Mean operative time was 35 ± 21 min (mean ± SD) and hospital stay was <24 h in all patients. Complete resolution of the narrowing at the PUJ under fluoroscopy was achieved in all cases, with no perioperative complications. One patient presented with urinary tract infection, postoperatively (Clavien grade II). Preoperatively, all cases had grade IV SFU hydronephrosis with parenchymal thinning. During follow-up, resolution of the hydronephrosis was observed in 11 patients (grade I SFU). In four infants, there was an improvement of the hydronephrosis (grade II SFU) and the renogram curve. In one case, an open pyeloplasty was required due to persistent hydronephrosis and obstructive curve.
We believe that endopyelotomy with cutting balloon could be a valid and safe option in minimally invasive management of UPJO in infants.
本研究旨在分析应用切割球囊逆行内切开术治疗婴儿肾盂输尿管连接部梗阻(UPJO)的结果。
我们常规治疗 18 个月以下 UPJO 患者采用逆行高压球囊扩张肾盂输尿管连接部(PUJ)。在这些病例中,如果 PUJ 狭窄仍然存在,则进行逆行内切开术治疗。在透视引导下,将导丝穿过 5mm 的切割球囊,进行内切开术。双 J 支架留置原位 4 周。我们回顾性分析了 2007 年至 2015 年间应用切割球囊行内切开术治疗的婴儿的术后、临床和影像学结果。
16 例患者需要切割球囊内切开术才能完全解决高压球囊扩张时观察到的肾盂输尿管连接部狭窄。平均手术时间为 35±21 分钟(均数±标准差),所有患者的住院时间均<24 小时。所有病例均在透视下完全解决了肾盂输尿管连接部的狭窄,无围手术期并发症。1 例术后发生尿路感染(Clavien Ⅱ级)。术前所有病例均有 SFU Ⅳ级积水伴肾实质变薄。随访期间,11 例积水消退(SFU Ⅰ级)。在 4 例婴儿中,积水(SFU Ⅱ级)和肾图曲线得到改善。1 例因持续性积水和梗阻性曲线而行开放肾盂成形术。
我们认为,应用切割球囊的内切开术可能是婴儿 UPJO 微创治疗的有效且安全的选择。