Department of Paediatric Urology, Gregorio Marañón University Hospital, Madrid, Spain.
Urology. 2013 Nov;82(5):1138-43. doi: 10.1016/j.urology.2013.04.072. Epub 2013 Aug 28.
To analyze the usefulness of dilatation in the treatment of ureteropelvic junction obstruction (UPJ) in children <18 months of age, including newborns and infants.
Patients (n = 50; <18 months of age) were diagnosed using abdominal ultrasound, cystogram, and diuretic renography. Treatment was with endourologic retrograde balloon dilatation under fluoroscopic guidance. The balloons were, in all cases, semicompliant with a profile of 5 mm, 6 mm, or 7 mm. Follow-up was for 42.9 ± 23.2 months (mean ± SD). Double-J stents were inserted postdilatation, the caliber and length depending on the patient's body weight.
Intervention duration was 22 ± 19 minutes. Dilatation was not possible in 5 patients, and pyeloplasty was the alternative treatment. Hospital stay was 24 hours in 44 patients. Analgesic needs were met exclusively by nonsteroidal anti-inflammatory drugs. The double-J stent was withdrawn using cystoscopy and the UPJ was calibrated.Residual stenosis was found in 7 patients. A second dilatation was required in 3 patients 6-18 months after surgery because of the lack of improvement of hydronephrosis. During follow-up, resolution of the hydronephrosis was observed in 45 cases (anterior-posterior diameter of the renal pelvis 7 ± 5 mm). The diuretic renography improved in 45 infants; the shape of the curve being normal in 44 cases and semi-obstructive in 1.
We believe that high-pressure balloon dilatation could be a valid and safe option in the minimally invasive treatment of UPJ obstruction in infants. The outcome is acceptable with a low complication rate.
分析在 <18 个月龄(包括新生儿和婴儿)的儿童中,使用扩张术治疗肾盂输尿管连接部梗阻(UPJ)的效果。
对 50 例(<18 个月龄)患者使用腹部超声、膀胱造影和利尿性肾动态显像进行诊断。在透视引导下进行经腔内逆行球囊扩张治疗。所有病例均使用半顺应性球囊,直径为 5mm、6mm 或 7mm。随访时间为 42.9±23.2 个月(均值±标准差)。扩张后插入双 J 支架,支架的口径和长度取决于患者的体重。
介入操作时间为 22±19 分钟。5 例患者因无法扩张而行肾盂成形术。44 例患者住院 24 小时。仅使用非甾体抗炎药即可满足镇痛需求。通过膀胱镜取出双 J 支架并校准 UPJ。7 例患者发现有残余狭窄。3 例患者在术后 6-18 个月因肾积水无改善而需要再次扩张。在随访期间,45 例患者的肾积水得到缓解(肾盂前后径为 7±5mm)。45 例婴儿利尿性肾动态显像得到改善,44 例曲线形态正常,1 例呈半梗阻性。
我们认为,高压球囊扩张术可能是治疗婴儿 UPJ 梗阻的一种有效且安全的微创选择。该方法并发症发生率低,治疗效果可接受。