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To be disordered or not to be disordered: is that still a question for proteins in the cell?无序还是有序：这对细胞中的蛋白质来说仍是个问题吗？
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本文引用的文献

1
SnapShot: Intrinsic Structural Disorder.快照：固有结构无序。
Cell. 2015 May 21;161(5):1230-1230.e1. doi: 10.1016/j.cell.2015.05.024.
2
Kinase dynamics. Using ancient protein kinases to unravel a modern cancer drug's mechanism.激酶动力学。利用古老的蛋白激酶来揭示一种现代癌症药物的作用机制。
Science. 2015 Feb 20;347(6224):882-6. doi: 10.1126/science.aaa1823.
3
Energetic dissection of Gleevec's selectivity toward human tyrosine kinases.积极解析格列卫对人源酪氨酸激酶的选择性。
Nat Struct Mol Biol. 2014 Oct;21(10):848-53. doi: 10.1038/nsmb.2891. Epub 2014 Sep 14.
4
Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease.Aβ 的瞬态动力学导致阿尔茨海默病的毒性。
Cell Mol Life Sci. 2014 Sep;71(18):3507-21. doi: 10.1007/s00018-014-1634-z. Epub 2014 May 7.
5
The triple power of D³: protein intrinsic disorder in degenerative diseases.D³ 的三重力量：退行性疾病中的蛋白质固有无序。
Front Biosci (Landmark Ed). 2014 Jan 1;19(2):181-258. doi: 10.2741/4204.

Editorial: Function and Flexibility: Friend or Foe?

作者信息

Pauwels Kris, Tompa Peter

机构信息

VIB Structural Biology Research Center, Vlaams Instituut voor BiotechnologieBrussels, Belgium; Structural Biology Brussels, Vrije Universiteit BrusselBrussels, Belgium.

VIB Structural Biology Research Center, Vlaams Instituut voor BiotechnologieBrussels, Belgium; Structural Biology Brussels, Vrije Universiteit BrusselBrussels, Belgium; Research Centre for Natural Sciences of the Hungarian Academy of Sciences, Institute of EnzymologyBudapest, Hungary.

出版信息

Front Mol Biosci. 2016 Jul 7;3:31. doi: 10.3389/fmolb.2016.00031. eCollection 2016.

DOI:10.3389/fmolb.2016.00031
PMID:27458588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4935808/
Abstract
摘要