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一例被忽视的甲状腺乳头状癌导致广泛喉部浸润的病例报告。

Extensive laryngeal infiltration from a neglected papillary thyroid carcinoma: A case report.

作者信息

Georgiades Fanourios, Vasiliou George, Kyrodimos Efthimios, Thrasyvoulou Giannis

机构信息

Fanourios Georgiades, St George's, University of London at the University of Nicosia, 2408 Nicosia, Cyprus.

出版信息

World J Clin Cases. 2016 Jul 16;4(7):187-90. doi: 10.12998/wjcc.v4.i7.187.

Abstract

Papillary carcinoma of the thyroid is the commonest type of thyroid cancer. Laryngeal infiltration from papillary thyroid carcinoma is extremely rare, with only a few cases of partial invasion described in the literature. We present a very unusual case of complete infiltration of both thyroid and cricoid cartilages from a neglected papillary thyroid carcinoma in a 59-year-old male. This sequel resulted from refusal of the patient to undergo treatment when initially diagnosed. An invasion to such an extent has not been described in the literature before, and in this case warranted a total laryngectomy followed by radioactive iodine. Prompt management of papillary carcinomas is crucial for avoiding such complications. Future guidelines should include management options for the patients who deny treatment initially.

摘要

甲状腺乳头状癌是甲状腺癌最常见的类型。甲状腺乳头状癌侵犯喉部极为罕见,文献中仅描述过少数几例局部侵犯的病例。我们报告了一例非常特殊的病例,一名59岁男性因被忽视的甲状腺乳头状癌导致甲状腺和环状软骨均被完全侵犯。这种后果是由于患者最初被诊断时拒绝接受治疗所致。如此程度的侵犯此前文献中未曾有过描述,在本病例中需要进行全喉切除术,随后进行放射性碘治疗。对甲状腺乳头状癌进行及时处理对于避免此类并发症至关重要。未来的指南应纳入针对最初拒绝治疗患者的处理方案。

相似文献

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Cartilage invasion patterns in laryngeal cancer.喉癌中的软骨浸润模式
Eur Arch Otorhinolaryngol. 2016 Jul;273(7):1863-9. doi: 10.1007/s00405-015-3687-5. Epub 2015 Jun 23.

本文引用的文献

1
Surgical Management of Cricotracheal Invasion by Papillary Thyroid Carcinoma.甲状腺乳头状癌侵犯环状气管的手术治疗
Ann Surg Oncol. 2015 Nov;22(12):4002-7. doi: 10.1245/s10434-015-4492-5. Epub 2015 Mar 19.
2
Guidelines for the management of thyroid cancer.甲状腺癌管理指南。
Clin Endocrinol (Oxf). 2014 Jul;81 Suppl 1:1-122. doi: 10.1111/cen.12515.
4
Classification of aerodigestive tract invasion from thyroid cancer.甲状腺癌所致的咽-气道侵犯分类。
Langenbecks Arch Surg. 2014 Feb;399(2):209-16. doi: 10.1007/s00423-013-1142-x. Epub 2013 Nov 24.

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