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神经科学:帕金森病患者决策能力受损

Neuroscience: Impaired Decision-Making in Parkinson's Disease.

作者信息

Herz Damian M, Bogacz Rafal, Brown Peter

机构信息

Medical Research Council Brain Network Dynamics Unit at the University of Oxford, Mansfield Road, Oxford, OX1 3TH, UK; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

出版信息

Curr Biol. 2016 Jul 25;26(14):R671-3. doi: 10.1016/j.cub.2016.05.075.

DOI:10.1016/j.cub.2016.05.075
PMID:27458912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4986883/
Abstract

When making decisions we combine previously acquired knowledge with the available current information to optimize our choices. A new study shows that Parkinson patients are impaired in using their prior knowledge leading to suboptimal decisions when current information is ambiguous.

摘要

在做决策时,我们会将先前获得的知识与现有的当前信息相结合,以优化我们的选择。一项新研究表明,帕金森病患者在运用其先前知识方面存在障碍,导致在当前信息模糊时做出次优决策。

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本文引用的文献

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Patients with Parkinson's Disease Show Impaired Use of Priors in Conditions of Sensory Uncertainty.帕金森病患者在感觉不确定的情况下表现出先验信息使用受损。
Curr Biol. 2016 Jul 25;26(14):1902-10. doi: 10.1016/j.cub.2016.05.039. Epub 2016 Jun 16.
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Neural Correlates of Decision Thresholds in the Human Subthalamic Nucleus.人类丘脑底核决策阈值的神经关联
Curr Biol. 2016 Apr 4;26(7):916-20. doi: 10.1016/j.cub.2016.01.051. Epub 2016 Mar 17.
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Mesolimbic dopamine signals the value of work.中脑边缘多巴胺传递工作的价值。
利用功能磁共振成像绘制神经经济学的神经基础:一篇叙述性文献综述。
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Neural Substrates of the Drift-Diffusion Model in Brain Disorders.脑部疾病中漂移扩散模型的神经基质
Front Comput Neurosci. 2022 Jan 7;15:678232. doi: 10.3389/fncom.2021.678232. eCollection 2021.
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Implicit and explicit learning of Bayesian priors differently impacts bias during perceptual decision-making.贝叶斯先验的内隐和外显学习对感知决策中的偏差有不同的影响。
Sci Rep. 2021 Aug 20;11(1):16932. doi: 10.1038/s41598-021-95833-7.
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Prefrontal Contributions to Attention and Working Memory.前额叶对注意力和工作记忆的作用。
Curr Top Behav Neurosci. 2019;41:129-153. doi: 10.1007/7854_2018_74.
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Anti-saccades predict cognitive functions in older adults and patients with Parkinson's disease.抗扫视任务可预测老年人和帕金森病患者的认知功能。
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Parkinson's disease.帕金森病。
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Cognitive deficits in Parkinson's disease: a cognitive neuroscience perspective.帕金森病的认知缺陷:认知神经科学视角。
Mov Disord. 2014 Apr 15;29(5):597-607. doi: 10.1002/mds.25853.
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Functional neuroimaging of motor control in Parkinson's disease: a meta-analysis.帕金森病运动控制的功能神经影像学:荟萃分析。
Hum Brain Mapp. 2014 Jul;35(7):3227-37. doi: 10.1002/hbm.22397. Epub 2013 Oct 5.
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J Neurosci. 2012 Nov 21;32(47):16716-24. doi: 10.1523/JNEUROSCI.1744-12.2012.
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Eur J Neurosci. 2012 Apr;35(7):1144-51. doi: 10.1111/j.1460-9568.2012.08043.x.
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The cost of accumulating evidence in perceptual decision making.在知觉决策中积累证据的成本。
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