小胶质细胞：吞噬以清除、塑造和消除。
Microglia: Phagocytosing to Clear, Sculpt, and Eliminate.
机构信息
F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
F.M. Kirby Neurobiology Center, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
出版信息
Dev Cell. 2016 Jul 25;38(2):126-8. doi: 10.1016/j.devcel.2016.07.006.
Microglia are the primary phagocytes of the central nervous system. They eliminate excess functional connections between neurons to sculpt neuronal circuits during development and throughout adulthood. Understanding how microglia recognize and prune synapses during development is providing insight into synapse loss and dysfunction in disease.
小胶质细胞是中枢神经系统的主要吞噬细胞。它们在发育过程中和成年后消除神经元之间多余的功能连接，塑造神经元回路。了解小胶质细胞在发育过程中如何识别和修剪突触，为研究疾病中突触丢失和功能障碍提供了线索。
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