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近距离工作对北京城市学生近视屈光变化的影响:一项三年随访报告

The influence of near work on myopic refractive change in urban students in Beijing: a three-year follow-up report.

作者信息

Lin Zhong, Vasudevan Balamurali, Mao Guang Yun, Ciuffreda Kenneth J, Jhanji Vishal, Li Xiao Xia, Zhou Hong Jia, Wang Ning Li, Liang Yuan Bo

机构信息

The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, No. 270 West College Road, Wenzhou, Zhejiang, 325027, China.

College of Optometry, Mid Western University, Glendale, AZ, USA.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2016 Nov;254(11):2247-2255. doi: 10.1007/s00417-016-3440-9. Epub 2016 Jul 26.

Abstract

PURPOSE

To investigate the influence of daily activities on myopic refractive change and myopic onset in Chinese urban students.

METHODS

The Beijing Myopia Progression Study was a 3-year cohort study. Cycloplegic refraction and a daily activity questionnaire were assessed at baseline and at follow-up examinations. Refractive change was defined as the difference in cycloplegic spherical equivalent (SE) between the final follow-up and baseline. 386 students were initially enrolled in the baseline study.

RESULTS

At the final follow-up, 222 students (57.5 %) with completed refractive error and daily activity data were analyzed. These students spent 0.32 ± 2.33 h/day more on near work (p = 0.04), and 0.21 ± 1.31 h/day less on outdoor leisure (p = 0.02), than they did at baseline. In the multivariate analysis, the younger among the secondary students (β = 0.06, p < 0.001), and those with more near work hours at baseline (β = -0.028, p = 0.033), exhibited more myopic refractive change. However, myopic refractive change was not found to be significantly associated with near work hours in the primary students, or with time spent outdoors, in either school level. After stratifying the activity hours into quartile groups, students with a greater near work load at baseline (trend P = 0.03) exhibited a greater myopic refractive change and had a higher risk to develop myopia (hazard ratio, 95 % confidence interval: 5.19, 1.49-18.13), after adjusting for the confounders. However, no significant association was found related to outdoor activity.

CONCLUSIONS

In this cohort, children with a greater near work load at baseline exhibited more myopic refractive change and were also more likely to develop myopia. The protective effect of outdoor activity on myopic refractive change was not observed.

摘要

目的

探讨日常活动对中国城市学生近视屈光变化及近视发生的影响。

方法

北京近视进展研究是一项为期3年的队列研究。在基线和随访检查时评估睫状肌麻痹验光和日常活动问卷。屈光变化定义为末次随访与基线时睫状肌麻痹等效球镜(SE)的差值。最初有386名学生纳入基线研究。

结果

在末次随访时,对222名(57.5%)完成屈光不正和日常活动数据的学生进行了分析。与基线时相比,这些学生每天近距工作时间多花0.32±2.33小时(p = 0.04),户外休闲时间少花0.21±1.31小时(p = 0.02)。在多因素分析中,中学生中年龄较小者(β = 0.06,p < 0.001)以及基线时近距工作时间较多者(β = -0.028,p = 0.033)表现出更多的近视屈光变化。然而,未发现小学生的近视屈光变化与近距工作时间显著相关,也未发现两个学龄段的近视屈光变化与户外活动时间显著相关。将活动时间分层为四分位数组后,在调整混杂因素后,基线时近距工作负荷较大的学生表现出更大的近视屈光变化,且发生近视的风险更高(风险比,95%置信区间:5.19,1.49 - 18.13)。然而,未发现与户外活动有显著关联。

结论

在该队列中,基线时近距工作负荷较大的儿童表现出更多的近视屈光变化,且更易发生近视。未观察到户外活动对近视屈光变化的保护作用。

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