Tian Rayna, MacGibbon Kimber, Martin Bhuvan, Mullin Patrick, Fejzo Marlena
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Hyperemesis Education and Research Foundation, Damascus, OR, United States.
Auton Neurosci. 2017 Jan;202:73-78. doi: 10.1016/j.autneu.2016.07.005. Epub 2016 Jul 20.
The purpose of this study is to determine the frequency of reporting of both pre-pregnancy and post-pregnancy psychosocial and physical issues in women with hyperemesis gravidarum (HG). Conditions in 449 women with HG were compared to 459 unaffected women (controls). Binary responses were analyzed using either Chi-squared or Fishers Exact test. Continuous responses were analyzed using a t-test. Among 60 pre-pregnancy conditions surveyed, 10 common (>5%) maternal pre-pregnancy conditions were significantly more frequently reported by women with HG. Twenty rare (<5% controls) pre-pregnancy conditions with significantly increased reporting in the HG group were identified. Thirty (50%) pre-pregnancy conditions were similarly reported between cases and controls. Among 80 post-pregnancy factors surveyed, women with HG also showed significantly higher reporting for 7 common and 50 rare post-pregnancy outcomes. Women with HG are significantly more likely to self-report physical and psychosocial issues both before and after pregnancy.
本研究的目的是确定妊娠剧吐（HG）女性孕前和孕后心理社会及身体问题的报告频率。将449例HG女性的情况与459例未受影响的女性（对照组）进行比较。二元反应采用卡方检验或费舍尔精确检验进行分析。连续反应采用t检验进行分析。在调查的60种孕前情况中，10种常见（>5%）的孕前母体情况在HG女性中报告的频率显著更高。确定了20种在HG组中报告显著增加的罕见（<5%对照组）孕前情况。病例组和对照组之间有30种（50%）孕前情况的报告相似。在调查的80种产后因素中，HG女性在7种常见和50种罕见产后结果方面的报告也显著更高。HG女性在孕前和孕后自我报告身体和心理社会问题的可能性显著更高。
