Bashiri A, Neumann L, Maymon E, Katz M
Department of Obstetrics and Gynecology, Soroka Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Eur J Obstet Gynecol Reprod Biol. 1995 Dec;63(2):135-8. doi: 10.1016/0301-2115(95)02238-4.
During the period of 4 years between 1985 and 1988, 190 patients suffering from hyperemesis gravidarum (HG) were hospitalized at the Soroka Medical Center. From the 190 patients, 164 were followed up throughout their pregnancies and delivered at our Medical Center. The epidemiology of HG as well as the incidence of maternal complications and pregnancy outcome were analyzed and compared with 209 controls. The incidence of HG in our patient population was 6.3/1000 live births. The patients in the study group had fewer pregnancies and deliveries and more spontaneous abortions in the past than in the control population. Premature contractions and vaginal bleeding during the first trimester were more common among women with HG. Other complications of pregnancy were no more common than among controls. Women with HG in their current pregnancy had a lower incidence of spontaneous abortions (3.1%) as compared with previously reported rates in the general population (15%). Perinatal outcome was no different in women with HG than in the controls. Women with severe HG did not have statistically significant differences in the incidence of pregnancy complications and their pregnancy outcome was the same as in those without severe HG.
在1985年至1988年的4年期间，190例妊娠剧吐（HG）患者在索罗卡医疗中心住院。这190例患者中，有164例在整个孕期接受了随访，并在我们的医疗中心分娩。对妊娠剧吐的流行病学、孕产妇并发症发生率及妊娠结局进行了分析，并与209例对照组进行了比较。我们研究人群中妊娠剧吐的发生率为6.3/1000活产。研究组患者过去的妊娠和分娩次数较少，自然流产次数比对照组更多。妊娠剧吐女性在孕早期出现的宫缩和阴道出血更为常见。其他妊娠并发症并不比对照组更常见。与一般人群先前报告的发生率（15%）相比，当前妊娠合并妊娠剧吐的女性自然流产发生率较低（3.1%）。妊娠剧吐女性的围产期结局与对照组无差异。重度妊娠剧吐女性在妊娠并发症发生率方面无统计学显著差异，其妊娠结局与非重度妊娠剧吐女性相同。
