Badr Lina Kurdahi, Zeineddine Mirvat Hasan, Abbas Hanan, Charafeddine Lama
Azusa Pacific University, 700 E. Foothill Ave., Azusa, CA 91701, USA.
Neonatal Netw. 2016;35(4):228-33. doi: 10.1891/0730-0832.35.4.228.
To determine if a foam septum protector prevents nasal injury in preterm infants receiving nasal heated humidified oxygen.
A retrospective before and after comparative design was used.
Medical records of 101 preterm infants receiving either nasal continuous positive airway pressure (NCPAP) or nasal intermittent positive pressure ventilation (NIPPV) were reviewed; 50 were in the control group and 51 were in the intervention group that had the NeoSeal septum protector applied. The groups were not different in terms of gender, birth weight, gestational age, days intubated, or on days on NCPAP/NIPPV. Skin condition of nares was scored daily using the Neonatal Skin Risk Assessment Scale (NSRAS).
Infants who had the NeoSeal applied had significantly less nasal injuries, OR = 4.08; 95% confidence interval (CI), 1.22-9.59; p = .01. The best predictors of nasal injury were gestational age and whether the NeoSeal was applied or not.
确定泡沫鼻中隔保护器能否预防接受经鼻加热湿化氧气治疗的早产儿发生鼻损伤。
采用回顾性前后对比设计。
回顾了101例接受经鼻持续气道正压通气(NCPAP)或经鼻间歇正压通气(NIPPV)的早产儿的病历;50例为对照组,51例为干预组,干预组应用了NeoSeal鼻中隔保护器。两组在性别、出生体重、胎龄、插管天数或接受NCPAP/NIPPV的天数方面无差异。每天使用新生儿皮肤风险评估量表(NSRAS)对鼻孔皮肤状况进行评分。
应用NeoSeal的婴儿鼻损伤明显较少,比值比(OR)=4.08;95%置信区间(CI)为1.22 - 9.59;p = 0.01。鼻损伤的最佳预测因素是胎龄以及是否应用了NeoSeal。