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全身用皮质类固醇预防支气管肺发育不良:为合适的婴儿选择合适的药物。

Systemic Corticosteroids for the Prevention of Bronchopulmonary Dysplasia: Picking the Right Drug for the Right Baby.

作者信息

Rostas Sara E, McPherson Christopher

机构信息

Brigham and Women's Hospital, 75 Francis Street, CWN 418, Boston, MA 02115, USA.

出版信息

Neonatal Netw. 2016;35(4):234-9. doi: 10.1891/0730-0832.35.4.234.

DOI:10.1891/0730-0832.35.4.234
PMID:27461202
Abstract

Bronchopulmonary dysplasia is a morbidity of prematurity with implications into adulthood on respiratory and neurologic health. Multiple risk factors contribute to the development of bronchopulmonary dysplasia leading to examination of various strategies of prevention. Systemic corticosteroids are one prevention strategy with a large body of data, creating an ongoing controversy regarding the risks and benefits of therapy. Careful consideration of the available data along with the clinical characteristics of the individual infant is required before using this powerful therapy.

摘要

支气管肺发育不良是一种早产并发症,对成年后的呼吸和神经健康有影响。多种风险因素导致支气管肺发育不良的发生,从而促使人们对各种预防策略进行研究。全身用皮质类固醇是一种有大量数据支持的预防策略,这使得关于该疗法的风险和益处一直存在争议。在使用这种强效疗法之前,需要仔细考虑现有数据以及个体婴儿的临床特征。

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Systemic Corticosteroids for the Prevention of Bronchopulmonary Dysplasia: Picking the Right Drug for the Right Baby.全身用皮质类固醇预防支气管肺发育不良:为合适的婴儿选择合适的药物。
Neonatal Netw. 2016;35(4):234-9. doi: 10.1891/0730-0832.35.4.234.
2
Postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia - Who might benefit?产后皮质类固醇预防或治疗支气管肺发育不良 - 谁可能受益?
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Pharmacotherapy for the Prevention of Bronchopulmonary Dysplasia: Can Anything Compete with Caffeine and Corticosteroids?预防支气管肺发育不良的药物治疗:有什么能与咖啡因和皮质类固醇相抗衡吗?
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Corticosteroids for the treatment and prevention of bronchopulmonary dysplasia.
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[The use of postnatal corticosteroid therapy in premature infants to prevent or treat bronchopulmonary dysplasia: current situation and recommendations].[早产儿使用产后皮质类固醇疗法预防或治疗支气管肺发育不良:现状与建议]
Arch Pediatr. 2010 Oct;17(10):1480-7. doi: 10.1016/j.arcped.2010.07.013. Epub 2010 Sep 22.
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Postnatal Corticosteroids To Prevent Bronchopulmonary Dysplasia.产后皮质类固醇预防支气管肺发育不良。
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Commentary on "Early (&lt;7 Days) Systemic Postnatal Corticosteroids for Prevention of Bronchopulmonary Dysplasia in Preterm Infants".关于“早期(<7天)全身性产后皮质类固醇预防早产儿支气管肺发育不良”的评论
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[Research advance in prevention and treatment of bronchopulmonary dysplasia in premature infants].[早产儿支气管肺发育不良的防治研究进展]
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Bronchopulmonary dysplasia: Myths of pharmacologic management.支气管肺发育不良:药物治疗的误区。
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An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk of bronchopulmonary dysplasia.产后全身应用皮质类固醇对早产儿死亡率和脑瘫影响的最新研究:支气管肺发育不良风险的效应修正
J Pediatr. 2014 Dec;165(6):1258-60. doi: 10.1016/j.jpeds.2014.07.049. Epub 2014 Sep 10.

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Influenza Other Respir Viruses. 2018 Sep;12(5):662-666. doi: 10.1111/irv.12561. Epub 2018 May 22.
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Respir Res. 2017 Mar 23;18(1):51. doi: 10.1186/s12931-017-0535-8.