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全身用皮质类固醇预防支气管肺发育不良:为合适的婴儿选择合适的药物。

Systemic Corticosteroids for the Prevention of Bronchopulmonary Dysplasia: Picking the Right Drug for the Right Baby.

作者信息

Rostas Sara E, McPherson Christopher

机构信息

Brigham and Women's Hospital, 75 Francis Street, CWN 418, Boston, MA 02115, USA.

出版信息

Neonatal Netw. 2016;35(4):234-9. doi: 10.1891/0730-0832.35.4.234.

Abstract

Bronchopulmonary dysplasia is a morbidity of prematurity with implications into adulthood on respiratory and neurologic health. Multiple risk factors contribute to the development of bronchopulmonary dysplasia leading to examination of various strategies of prevention. Systemic corticosteroids are one prevention strategy with a large body of data, creating an ongoing controversy regarding the risks and benefits of therapy. Careful consideration of the available data along with the clinical characteristics of the individual infant is required before using this powerful therapy.

摘要

支气管肺发育不良是一种早产并发症,对成年后的呼吸和神经健康有影响。多种风险因素导致支气管肺发育不良的发生,从而促使人们对各种预防策略进行研究。全身用皮质类固醇是一种有大量数据支持的预防策略,这使得关于该疗法的风险和益处一直存在争议。在使用这种强效疗法之前,需要仔细考虑现有数据以及个体婴儿的临床特征。

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