Zhou Wenjuan, Yang Xiangcheng, Dai Yunyun, Wu Qihui, He Guoping, Yin Gang
Department of Humanistic Nursing, Xiangya School of Nursing, Central South University; Department of Pathology, School of Basic Medicine, Central South University, Changsha, Hunan 410013, P. R. China.
Department of Orthopedics, Zhuzhou Central Hospital, The Affiliated Zhuzhou Hospital Xiangya School of Medicine, Central South University, Zhuzhou, Hunan 412007, P. R. China.
J Cancer Res Ther. 2016 Apr-Jun;12(2):938-44. doi: 10.4103/0973-1482.175427.
To investigate the quality of life (QOL) of cervical cancer survivors in China.
Cervical cancer survivors were selected from 4 Tertiary Provincial Hospitals in Changsha, Hunan Province. Enrolled were 140 patients who received cancer treatments in these hospitals from 2007 to 2010. The Functional Assessment of Cancer Therapy-Cervix (FACT-Cx) Questionnaire was used to assess the QOL of the participants. Spiritual well-being was evaluated with the Functional Assessment of Chronic Illness Therapy-Spiritual Well-being (FACIT-Sp). Sexual function was measured with the Female Sexual Functioning Index.
The average total FACT-Cx score was 124.45 (70-157). The average FACT-general score was 112.39 (49-150), and the average FACIT-Sp score was 13.9 (2-33.6). The prevalence of sexual dysfunction in our participants was 78%. Factors that were associated with QOL in cervical cancer survivors included gastrointestinal symptoms, health insurance, age, sleep disorders, and the number of complications. Sexual function was affected by radiotherapy, age, type of surgery, sleep disorders, and occupation.
The QOL and sexual function of cervical cancer survivors were lower than the general population. Treatment-related complications and sexual dysfunction significantly affected patients' QOL. Having health insurance was associated with better QOL. Sexual function was adversely affected by radiotherapy and radical hysterectomy.
调查中国宫颈癌幸存者的生活质量(QOL)。
从湖南省长沙市4家省级三甲医院选取宫颈癌幸存者。纳入2007年至2010年期间在这些医院接受癌症治疗的140例患者。采用癌症治疗功能评价量表-宫颈癌(FACT-Cx)问卷评估参与者的生活质量。使用慢性病治疗功能评价量表-精神健康(FACIT-Sp)评估精神健康状况。采用女性性功能指数测量性功能。
FACT-Cx总评分平均为124.45(70 - 157)。FACT-通用量表评分平均为112.39(49 - 150),FACIT-Sp评分平均为13.9(2 - 33.6)。参与者性功能障碍的患病率为78%。与宫颈癌幸存者生活质量相关的因素包括胃肠道症状、医疗保险、年龄、睡眠障碍和并发症数量。性功能受放疗、年龄、手术类型、睡眠障碍和职业的影响。
宫颈癌幸存者的生活质量和性功能低于一般人群。与治疗相关的并发症和性功能障碍显著影响患者的生活质量。拥有医疗保险与较好的生活质量相关。放疗和根治性子宫切除术对性功能有不利影响。