Soden Peter A, Zettervall Sara L, Ultee Klaas H J, Darling Jeremy D, McCallum John C, Hamdan Allen D, Wyers Mark C, Schermerhorn Marc L
Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass.
Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass; Division of Surgery, George Washington University, Washington, D.C.
J Vasc Surg. 2017 Feb;65(2):362-371. doi: 10.1016/j.jvs.2016.04.066. Epub 2016 Jul 25.
The targeted vascular module in the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) consists of self-selected hospitals that choose to collect extra clinical details for better risk adjustment and improved procedure-specific outcomes. The purpose of this study was to compare patient selection and outcomes between targeted and nontargeted hospitals in the NSQIP regarding the operative management of abdominal aortic aneurysm (AAA).
We identified all patients who underwent endovascular aneurysm repair (EVAR) or open AAA repair from 2011 to 2013 and compared cases by whether the operation took place in a targeted or nontargeted hospital. EVAR and open repair as well as intact and ruptured aneurysms were evaluated separately. Only variables contained in both modules were used to evaluate rupture status and operation type. All thoracoabdominal aneurysms were excluded. Univariate analysis was performed for intact and ruptured EVAR and open repair grouped by complexity, defined as visceral involvement in open repair and a compilation of concomitant procedures for EVAR. Multivariable models were developed to identify effect of hospital type on mortality.
There were 17,651 AAA repairs identified. After exclusion of aneurysms involving the thoracic aorta (n = 352), there were 1600 open AAA repairs at targeted hospitals (21% ruptured) and 2725 at nontargeted hospitals (19% ruptured) and 4986 EVARs performed at targeted hospitals (6.7% ruptured) and 7988 at nontargeted hospitals (5.2% ruptured). There was no significant difference in 30-day mortality rates between targeted and nontargeted hospitals for intact aneurysms (EVAR noncomplex, 1.8% vs 1.4% [P = .07]; open repair noncomplex, 4.2% vs 4.5% [P = .7]; EVAR complex, 5.0% vs 3.2% [P = .3]; open repair complex, 8.0% vs 6.0% [P = .2]). For ruptured aneurysms, again there was no difference in mortality between the targeted and nontargeted hospitals (EVAR noncomplex, 23% vs 25% [P = .4]; open repair noncomplex, 38% vs 34% [P = .2]; EVAR complex, 29% vs 33% [P = 1.0]; open repair complex, 27% vs 41% [P = .09]). Multivariable analysis further demonstrated that having an operation at a targeted vs nontargeted hospital had no impact on mortality for both intact and ruptured aneurysms (odds ratio, 1.1 [0.9-1.4] and 1.0 [0.8-1.3], respectively).
This analysis highlights the similarities between targeted and nontargeted hospitals within the NSQIP for AAA operative management and suggests that data from the targeted NSQIP, in terms of AAA management, are generalizable to all NSQIP hospitals.
美国外科医师学会国家外科质量改进计划(NSQIP)中的目标血管模块由自行选择的医院组成,这些医院选择收集额外的临床细节,以更好地进行风险调整并改善特定手术的结果。本研究的目的是比较NSQIP中目标医院和非目标医院在腹主动脉瘤(AAA)手术管理方面的患者选择和结果。
我们确定了2011年至2013年期间所有接受血管内动脉瘤修复术(EVAR)或开放性AAA修复术的患者,并根据手术是在目标医院还是非目标医院进行,对病例进行比较。分别评估了EVAR和开放性修复以及完整和破裂的动脉瘤情况。仅使用两个模块中都包含的变量来评估破裂状态和手术类型。所有胸腹主动脉瘤均被排除。对按复杂性分组的完整和破裂EVAR及开放性修复进行单因素分析,复杂性定义为开放性修复中的内脏受累情况以及EVAR中的伴随手术汇总情况。建立多变量模型以确定医院类型对死亡率的影响。
共确定了17651例AAA修复手术。排除累及胸主动脉的动脉瘤(n = 352)后,目标医院有1600例开放性AAA修复术(21%破裂),非目标医院有2725例(19%破裂);目标医院进行了4986例EVAR手术(6.7%破裂),非目标医院进行了7988例(5.2%破裂)。完整动脉瘤的目标医院和非目标医院30天死亡率无显著差异(非复杂性EVAR,1.8%对1.4%[P = 0.07];非复杂性开放性修复,4.2%对4.5%[P = 0.7];复杂性EVAR,5.0%对3.2%[P = 0.3];复杂性开放性修复,8.0%对6.0%[P = 0.2])。对于破裂的动脉瘤病例,目标医院和非目标医院的死亡率也没有差异(非复杂性EVAR,23%对25%[P = 0.4];非复杂性开放性修复,38%对34%[P = 0.2];复杂性EVAR,29%对33%[P = 1.0];复杂性开放性修复,27%对41%[P = 0.09])多变量分析进一步表明,在目标医院与非目标医院进行手术,对完整和破裂动脉瘤死亡率均无影响(优势比分别为1.1[0.9 - 1.4]和1.0[0.8 - 1.3])。
该分析突出了NSQIP中目标医院和非目标医院在AAA手术管理方面的相似性,并表明就AAA管理而言,目标NSQIP的数据可推广至所有NSQIP医院。