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经皮穿刺与开放股动脉切开入路用于破裂腹主动脉瘤血管腔内修复的比较。

Comparison of percutaneous versus open femoral cutdown access for endovascular repair of ruptured abdominal aortic aneurysms.

作者信息

Chen Samuel L, Kabutey Nii-Kabu, Whealon Matthew D, Kuo Isabella J, Fujitani Roy M

机构信息

Division of Vascular and Endovascular Surgery, Department of Surgery, University of California, Irvine Medical Center, Orange, Calif.

Division of Vascular and Endovascular Surgery, Department of Surgery, University of California, Irvine Medical Center, Orange, Calif.

出版信息

J Vasc Surg. 2017 Nov;66(5):1364-1370. doi: 10.1016/j.jvs.2017.03.431.

Abstract

OBJECTIVE

Ruptured endovascular aortic aneurysm repair (REVAR) is being increasingly used to treat ruptured abdominal aortic aneurysms (rAAAs). However, the comparison between totally percutaneous (pREVAR) vs femoral cutdown (cREVAR) access for REVAR has not been studied. We used a national surgical database to evaluate the 30-day outcomes in patients undergoing pREVAR vs cREVAR.

METHODS

Patients who underwent EVAR for rAAA between 2011 and 2014, inclusively, were studied in the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) targeted vascular database. Univariate and multivariate analyses were used to compare preoperative demographics, operation-specific variables, and postoperative outcomes between those who had pREVAR and cREVAR.

RESULTS

We identified 502 patients who underwent REVAR, of which 129 had pREVAR (25.7%) and 373 cREVAR (74.3%). Between 2011 and 2014, the use of totally percutaneous access for repair increased from 14% to 32%. Of all patients undergoing REVAR, 24% had bilateral percutaneous access, 2% had attempted percutaneous access converted to cutdown, 64% had bilateral femoral cutdowns, and 10% had single femoral cutdown. Univariate analysis showed there were no significant differences in age, gender, body mass index, AAA size, or other high-risk physiologic comorbidities between the two groups. There was also no difference in rates of preoperative hemodynamic instability (48.1% vs 45.0%; P = .55) or need for perioperative transfusion (67.4% vs 67.8%; P = .94). There was a higher incidence of use of regional anesthesia for pREVAR compared with cREVAR (20.9% vs 7.8%; P < .01). The incidence of postoperative wound complications was similar between both groups (4.8% vs 5.4%; P = .79), whereas hospital length of stay was shorter in the pREVAR group (mean difference, 1.3 days). Overall 30-day mortality was higher in the pREVAR group (28.7% vs 20.1%; P = .04), and operative time was longer (mean difference, 6.3 minutes). However, when pREVARs done in 2011 to 2012 were compared with those done in 2013 to 2014, 30-day mortality decreased from 38.2% to 25.3% and operative time decreased by 25 minutes (188 to 163 minutes). Multivariate analysis showed there were no significant differences in mortality, wound complications, hospital length of stay, or operative time between pREVAR and cREVAR.

CONCLUSIONS

The ACS NSQIP targeted vascular database shows that there has been increased adoption of pREVAR in recent years, with improved mortality and operative time over the 4-year study period. At this point, pREVAR has not yet been shown to be superior to cREVAR for rAAA, but these outcome improvements are encouraging and likely attributable to increased operator experience.

摘要

目的

血管腔内修复术治疗破裂性腹主动脉瘤(REVAR)越来越多地用于治疗破裂性腹主动脉瘤(rAAA)。然而,完全经皮入路(pREVAR)与股动脉切开入路(cREVAR)在REVAR中的比较尚未得到研究。我们使用一个全国性的手术数据库来评估接受pREVAR与cREVAR治疗的患者的30天结局。

方法

对2011年至2014年(含)期间接受rAAA的血管腔内修复术(EVAR)的患者在美国外科医师学会(ACS)国家外科质量改进计划(NSQIP)的靶向血管数据库中进行研究。采用单因素和多因素分析比较接受pREVAR和cREVAR治疗的患者的术前人口统计学、手术相关变量和术后结局。

结果

我们确定了502例接受REVAR治疗的患者,其中129例采用pREVAR(25.7%),373例采用cREVAR(74.3%)。在2011年至2014年期间,完全经皮入路修复术的使用率从14%增加到32%。在所有接受REVAR治疗的患者中,24%采用双侧经皮入路,2%尝试经皮入路转为切开入路,64%采用双侧股动脉切开入路,10%采用单侧股动脉切开入路。单因素分析显示,两组患者在年龄、性别、体重指数、腹主动脉瘤大小或其他高危生理合并症方面无显著差异。术前血流动力学不稳定发生率(48.1%对45.0%;P = 0.55)或围手术期输血需求(67.4%对67.8%;P = 0.94)也无差异。与cREVAR相比,pREVAR采用区域麻醉的发生率更高(20.9%对7.8%;P < 0.01)。两组术后伤口并发症发生率相似(4.8%对5.4%;P = 0.79),而pREVAR组住院时间更短(平均差异1.3天)。总体30天死亡率在pREVAR组更高(28.7%对20.1%;P = 0.04),手术时间更长(平均差异6.3分钟)。然而,将2011年至2012年进行的pREVAR与2013年至2014年进行的pREVAR进行比较时,30天死亡率从38.2%降至25.3%,手术时间减少了25分钟(从188分钟降至163分钟)。多因素分析显示,pREVAR和cREVAR在死亡率、伤口并发症、住院时间或手术时间方面无显著差异。

结论

ACS NSQIP靶向血管数据库显示,近年来pREVAR的采用率有所增加,在4年的研究期间死亡率和手术时间有所改善。目前,对于rAAA,pREVAR尚未显示优于cREVAR,但这些结局的改善令人鼓舞,可能归因于手术医生经验的增加。

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