Mampalam T J, Rosegay H, Andrews B T, Rosenblum M L, Pitts L H
Department of Neurological Surgery, School of Medicine, University of California, San Francisco.
J Neurosurg. 1989 Aug;71(2):208-10. doi: 10.3171/jns.1989.71.2.0208.
Spinal epidural infections were diagnosed before the onset of neurological deficits in six patients and treated nonsurgically. The diagnosis was based on the clinical presentation and on the results of myelography and computerized tomography scanning. Positive cultures were obtained from blood in all six patients, from aspiration of a paraspinous infection in two, and from a skin abscess and a pulmonary empyema in one patient each. Staphylococcus aureus was the causative organism in five cases. All patients were treated with intravenous antibiotics and remained neurologically intact throughout the course of treatment. Five patients have had no recurrence of their symptoms. One patient eventually required surgery for persistent discitis.
6例患者在出现神经功能缺损之前被诊断为脊柱硬膜外感染,并接受了非手术治疗。诊断基于临床表现以及脊髓造影和计算机断层扫描结果。所有6例患者血液培养均为阳性,2例经椎旁感染穿刺培养阳性,1例皮肤脓肿和1例肺脓肿培养阳性。5例的致病菌为金黄色葡萄球菌。所有患者均接受静脉抗生素治疗,治疗过程中神经功能均保持完好。5例患者症状未复发。1例患者因持续性椎间盘炎最终需要手术治疗。