Gürer Gülcan, Bozbas Gulnur Tasci, Tuncer Tiraje, Unubol Ayse Iyiyapici, Ucar Ulku Gurbuz, Memetoglu Ozge Illeez
Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Adnan Menderes University School of Medicine, Aydin, Turkey.
Department of Physical Medicine and Rehabilitation, Akdeniz University School of Medicine, Antalya, Turkey.
Int J Rheum Dis. 2018 Oct;21(10):1787-1792. doi: 10.1111/1756-185X.12883. Epub 2016 Jul 27.
Osteoarthritis (OA) of the knee is one of the major causes of joint dysfunction and physically disabling conditions in the older population. The risk factors for the development of knee OA are very diverse. We aimed to determine the frequency of joint hypermobility in patients with knee OA.
Five hundred and three patients (402 female and 101 male) with bilateral knee OA were enrolled in five different clinics from three regions of Turkey. In this study, joint hypermobility was evaluated in the participants by using the Beighton scoring system and a Beighton score of at least 4 was considered as joint hypermobility. Radiological scoring was performed according to Kellgren and Lawrence.
The percentages of generalized joint hypermobility were determined as 21.5% in all of the patients, 23.9% in female patients and 11.9% in male patients. The percentage of hypermobility (67.9%) was found to be highest in patients with knee OA aged between 22-30 years as against other age groups. Highest hypermobility percentage was found as 73.9% (17/23) in female patients and as 40% (2/5) in male patients between 22-30 years. The hypermobility of knee was found to have the highest frequency in patients aged between 22-40 years as compared to other joint regions and also to be second-highest frequency in all patients aged between 41-92 years. As a result, generalized joint hypermobility was determined to be of high frequency in patients with knee OA. Furthermore, we have seen that knee mobility was established to be of considerably high frequency in patients with knee OA.
This study showed generalized joint hypermobility and knee hypermobility may be associated with knee OA. According to the results of this study, we can suggest that generalized joint hypermobility and also knee hypermobility may increase the risk of knee OA. According to this study, it should be considered that knee OA will develop in individuals who have generalized joint hypermobility and these individuals should be educated from this point before OA it occurs.
膝关节骨关节炎（OA）是老年人群关节功能障碍和身体致残的主要原因之一。膝关节OA发生的风险因素非常多样。我们旨在确定膝关节OA患者关节活动度过大的发生率。
来自土耳其三个地区的五家不同诊所招募了503例双侧膝关节OA患者（402例女性和101例男性）。在本研究中，采用Beighton评分系统对参与者的关节活动度过大进行评估，Beighton评分至少为4分被视为关节活动度过大。根据Kellgren和Lawrence进行放射学评分。
所有患者中全身关节活动度过大的百分比为21.5%，女性患者为23.9%，男性患者为11.9%。与其他年龄组相比，22 - 30岁的膝关节OA患者中活动度过大的百分比（67.9%）最高。22 - 30岁女性患者中活动度过大的百分比最高，为73.9%（17/23），男性患者为40%（2/5）。与其他关节区域相比，22 - 40岁患者膝关节活动度过大的频率最高，在41 - 92岁的所有患者中频率也排第二。结果表明，膝关节OA患者中全身关节活动度过大的频率较高。此外，我们发现膝关节OA患者中膝关节活动度较大的频率也相当高。
本研究表明全身关节活动度过大和膝关节活动度过大可能与膝关节OA有关。根据本研究结果，我们可以认为全身关节活动度过大和膝关节活动度过大可能会增加膝关节OA的风险。根据本研究，应考虑到全身关节活动度过大的个体可能会发生膝关节OA，并且应在OA发生之前从这一点对这些个体进行教育。
