Junge Tina, Henriksen Peter, Hansen Sebrina, Østengaard Lasse, Golightly Yvonne M, Juul-Kristensen Birgit
Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Health Sciences Research Centre, University College Lillebaelt, Odense, Denmark.
Int J Rheum Dis. 2019 Feb;22(2):288-296. doi: 10.1111/1756-185X.13205. Epub 2017 Oct 27.
Several biomechanical factors, such as knee joint hypermobility (KJH), are suggested to play a role in the etiology of knee joint symptoms and knee osteoarthritis. Nevertheless, the prevalence or consequences of KJH solely or included in the classification of generalized joint hypermobility (GJHk) is unknown for a general population. Therefore, the objectives were to report the prevalence of self-reported GJHk and KJH, as well as the association of these conditions to knee joint symptoms, severity and duration of symptoms, and health-related quality of life (HRQoL) in a Danish adult population.
This study is a cross-sectional population-based survey of 2056 Danish adults. Respondents received online questionnaires of GJHk and KJH, knee joint symptoms, the severity and duration of these, as well as HRQoL.
Total response rate was 49% (n = 1006). The prevalence of self-reported GJHk and KJH was 13% and 23%, mostly representing women. More than half of the respondents with GJHk and KJH had knee joint symptoms. The odds for reporting knee joint symptoms, severity of knee joint symptoms and duration of knee joint symptoms were twice as high for respondents with GJHk and KJH. Respondents with GJHk and KJH reported lower HRQoL.
GJHk and KJH were frequently reported in the Danish adult population, mostly in women. Respondents with GJHk and KJH were two times more likely to report knee joint-related symptoms such as pain, reduced performance of usual activity and lower HRQoL. The impact of these conditions on HRQoL is comparable with knee osteoarthritis.
有几种生物力学因素，如膝关节活动度过大（KJH），被认为在膝关节症状和膝骨关节炎的病因中起作用。然而，对于一般人群而言，单纯的KJH或纳入广义关节活动度过大（GJHk）分类中的KJH的患病率或后果尚不清楚。因此，本研究的目的是报告丹麦成年人群中自我报告的GJHk和KJH的患病率，以及这些情况与膝关节症状、症状的严重程度和持续时间以及健康相关生活质量（HRQoL）之间的关联。
本研究是一项基于人群的横断面调查，共纳入2056名丹麦成年人。受访者通过在线问卷报告GJHk和KJH、膝关节症状、症状的严重程度和持续时间以及HRQoL。
总应答率为49%（n = 1006）。自我报告的GJHk和KJH的患病率分别为13%和23%，大多数为女性。超过一半的GJHk和KJH受访者有膝关节症状。GJHk和KJH受访者报告膝关节症状、膝关节症状严重程度和膝关节症状持续时间的几率是其他人的两倍。GJHk和KJH受访者报告的HRQoL较低。
丹麦成年人群中经常报告GJHk和KJH情况，大多数为女性。GJHk和KJH受访者报告膝关节相关症状（如疼痛、日常活动能力下降）以及HRQoL较低的可能性是其他人的两倍。这些情况对HRQoL的影响与膝骨关节炎相当。
