Pang Xiaofeng, Chen Shude, Wang Xianghui, Zhong Lisheng
Institute of Physical Electrons, University of Electronic Science and Technology of China, Chengdu 610054, China.
Department of Physics, East China Normal University, Shanghai 200062, China.
Int J Mol Sci. 2016 Jul 25;17(8):1130. doi: 10.3390/ijms17081130.
The influences of electromagnetic fields (EMFs) on bio-energy transport and its mechanism of changes are investigated through analytic and numerical simulation and experimentation. Bio-energy transport along protein molecules is performed by soliton movement caused by the dipole-dipole electric interactions between neighboring amino acid residues. As such, EMFs can affect the structure of protein molecules and change the properties of the bio-energy transported in living systems. This mechanism of biological effect from EMFs involves the amino acid residues in protein molecules. To study and reveal this mechanism, we simulated numerically the features of the movement of solitons along protein molecules with both a single chain and with three channels by using the Runge-Kutta method and Pang's soliton model under the action of EMFs with the strengths of 25,500, 51,000, 76,500, and 102,000 V/m in the single-chain protein, as well as 17,000, 25,500, and 34,000 V/m in the three-chain protein, respectively. Results indicate that electric fields (EFs) depress the binding energy of the soliton, decrease its amplitude, and change its wave form. Also, the soliton disperses at 102,000 V/m in a single-chain protein and at 25,500 and 34,000 V/m in three-chain proteins. These findings signify that the influence of EMFs on the bio-energy transport cannot be neglected; however, these variations depend on both the strength and the direction of the EF in the EMF. This direction influences the biological effects of EMF, which decrease with increases in the angle between the direction of the EF and that of the dipole moment of amino acid residues; however, randomness at the macroscopic level remains. Lastly, we experimentally confirm the existence of a soliton and the validity of our conclusion by using the infrared spectra of absorption of the collagens, which is activated by another type of EF. Thus, we can affirm that both the described mechanism and the corresponding theory are correct and that EMFs or EFs can influence the features of energy transport in living systems and thus have certain biological effects.
通过分析、数值模拟和实验研究了电磁场（EMFs）对生物能量传输的影响及其变化机制。生物能量沿蛋白质分子的传输是由相邻氨基酸残基之间的偶极 - 偶极电相互作用引起的孤子运动来实现的。因此，电磁场可以影响蛋白质分子的结构，并改变生物系统中传输的生物能量的性质。电磁场的这种生物效应机制涉及蛋白质分子中的氨基酸残基。为了研究和揭示这种机制，我们使用龙格 - 库塔方法和庞氏孤子模型，在强度分别为25500、51000、76500和102000 V/m的电磁场作用下，对单链蛋白质以及三链蛋白质中孤子沿蛋白质分子运动的特征进行了数值模拟。在单链蛋白质中，电磁场强度分别为上述值；在三链蛋白质中，电磁场强度分别为17000、25500和34000 V/m。结果表明，电场（EFs）降低了孤子的结合能，减小了其振幅，并改变了其波形。此外，在单链蛋白质中，孤子在102000 V/m时会分散；在三链蛋白质中，孤子在25500和34000 V/m时会分散。这些发现表明，电磁场对生物能量传输的影响不可忽视；然而，这些变化取决于电磁场中电场的强度和方向。这个方向会影响电磁场的生物效应，随着电场方向与氨基酸残基偶极矩方向之间夹角的增大，生物效应会减小；然而，宏观层面上仍存在随机性。最后，我们通过使用由另一种类型电场激活的胶原蛋白的红外吸收光谱，实验证实了孤子的存在以及我们结论的有效性。因此，我们可以肯定，所描述的机制和相应理论是正确的，并且电磁场或电场可以影响生物系统中能量传输的特征，从而具有一定的生物效应。
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