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[一例鼻咽部淀粉样变性病例]

[A case of nasopharyngeal amyloidosis].

作者信息

Kumagami H, Matzumura T, Aoki S

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 1989 Feb;92(2):165-8. doi: 10.3950/jibiinkoka.92.165.

Abstract

A case of amyloidosis localized in the nasopharynx was reported. The patient was a 62-year-old female who complained of persistent nasal obstruction. The gross appearance of this tumor showed a thumb-sized red-yellowish mass, in part covered with white coating. The systemic amyloidosis was excluded by several clinical examinations including rectal biopsy. Histopathological examination revealed diffuse deposits of homogeneous eosinophilic substances. A polarized microscopic examination by congo-red stain showed that deposit's substances were amyloid. A typical amyloid fibril was observed under electron microscope. The mass was removed with Beckmann adenotome. Bleeding was minimal.

摘要

报告了一例局限于鼻咽部的淀粉样变性病例。患者为一名62岁女性,主诉持续性鼻塞。该肿瘤大体表现为拇指大小的红黄相间肿物,部分覆盖有白色被膜。通过包括直肠活检在内的多项临床检查排除了系统性淀粉样变性。组织病理学检查显示均匀嗜酸性物质的弥漫性沉积。刚果红染色的偏振显微镜检查显示沉积物为淀粉样物质。在电子显微镜下观察到典型的淀粉样纤维。用贝克曼鼻窦刀切除肿物。出血极少。

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