Department of Cardiology, Flinders University, Adelaide, SA
Department of Internal Medicine, Princess Alexandra Hospital, Brisbane, QLD.
Med J Aust. 2016 Aug 1;205(3):128-33. doi: 10.5694/mja16.00368.
The modern care of suspected and confirmed acute coronary syndrome (ACS) is informed by an extensive and evolving evidence base. This clinical practice guideline focuses on key components of management associated with improved clinical outcomes for patients with chest pain or ACS. These are presented as recommendations that have been graded on both the strength of evidence and the likely absolute benefit versus harm. Additional considerations influencing the delivery of specific therapies and management strategies are presented as practice points.
This guideline provides advice on the standardised assessment and management of patients with suspected ACS, including the implementation of clinical assessment pathways and subsequent functional and anatomical testing. It provides guidance on the: diagnosis and risk stratification of ACS; provision of acute reperfusion therapy and immediate post-fibrinolysis care for patients with ST segment elevation myocardial infarction; risk stratification informing the use of routine versus selective invasive management for patients with non-ST segment elevation ACS; administration of antithrombotic therapies in the acute setting and considerations affecting their long term use; and implementation of an individualised secondary prevention plan that includes both pharmacotherapies and cardiac rehabilitation. Changes in management as a result of the guideline: This guideline has been designed to facilitate the systematic integration of the recommendations into a standardised approach to ACS care, while also allowing for contextual adaptation of the recommendations in response to the individual's needs and preferences. The provision of ACS care should be subject to continuous monitoring, feedback and improvement of quality and patient outcomes.
现代对疑似和确诊急性冠状动脉综合征(ACS)的治疗是基于广泛而不断发展的证据基础。本临床实践指南重点关注与改善胸痛或 ACS 患者临床结局相关的管理的关键组成部分。这些建议是根据证据强度和可能的绝对获益与危害进行分级的。还提出了影响特定治疗和管理策略实施的其他考虑因素作为实践要点。
本指南就疑似 ACS 患者的标准化评估和管理提供建议,包括临床评估途径的实施以及随后的功能和解剖学测试。它提供了以下方面的指导:ACS 的诊断和风险分层;ST 段抬高型心肌梗死患者的急性再灌注治疗和溶栓后即刻护理;非 ST 段抬高型 ACS 患者常规与选择性有创性管理的风险分层指导;急性治疗中抗血栓治疗的应用以及影响其长期使用的因素;以及个体化二级预防计划的实施,包括药物治疗和心脏康复。
本指南旨在促进将建议系统地纳入 ACS 治疗的标准化方法,同时允许根据个人的需求和偏好对建议进行情境适应性调整。ACS 护理的提供应受到持续监测、反馈和质量以及患者结局的改进。