Kahn M F, Bourgeois P, Aeschlimann A, de Truchis P
Clinique de Rhumatologie, Faculté Xavier Bichat, Université Paris VII, France.
J Rheumatol. 1989 Apr;16(4):533-5.
We present 4 patients fulfilling criteria for mixed connective tissue disease (MCTD) with anti-RNP antibodies, who had been previously exposed, in 4 different professions, to polyvinyl chloride. This presentation is clinically and serologically different from the classical polyvinyl chloride disease in which no such antibody can be found. Already observed in patients after cosmetic surgery, MCTD could also be a result of toxic exposure.
我们报告了4例符合混合性结缔组织病（MCTD）标准且伴有抗RNP抗体的患者，他们曾在4种不同职业中接触过聚氯乙烯。这种表现与经典的聚氯乙烯疾病在临床和血清学上有所不同，后者无法检测到此类抗体。MCTD在接受整容手术的患者中已有发现，它也可能是有毒物质暴露的结果。
